Bioequivalence and Bioavailability Forum

Quasi-synonyms [Power / Sample Size]

posted by d_labes  – Berlin, Germany, 2012-02-10 16:18 (5250 d 09:09 ago) – Posting: # 8100
Views: 5,794

Dear Outlaw

❝ Which method is right for a clinical trial to test equivalence of a generic to a reference product—proportions or binomial?

Proportions are distributed according to binomial distribution (or if the events you are observing are very rare according to the Poisson distribution).
So if you talk about comparison of proportions you talk about comparisons of binomial outcomes.

Hope this doesn't add to your beer thirst .
Have a nice weekend.

Complete thread:

• Sampe size calculations The Outlaw Torn 2012-02-09 12:04 
  • Sampe size for equivalence of proportions d_labes 2012-02-10 09:28
    • Sampe size for equivalence of proportions The Outlaw Torn 2012-02-10 11:59
      • Going to Pup before cataclysm d_labes 2012-02-10 13:10
        • Going to Pup before cataclysm The Outlaw Torn 2012-02-10 14:18
          • Quasi-synonymsd_labes 2012-02-10 15:18