Log in
RegisterCredibility of data [Power / Sample Size]
Dear HS,
Thank you very much for your explaination.
If the study is well designed and conducted in standardised and controlled manner, i believe that the variability due to design issues, clinical setting and analytical method is very less or negligible.
Regards,
Skar
Thank you very much for your explaination.
❝ ❝ The intra-subject CV is due to drug and formulation.
❝ Not quite. You should also consider
- design issues (number and location of sampling time points, single dose vs. steady state),
- clinical setting (food, posture, physical activity), and
- analytical variability (mainly stability and to a lesser degree the method itself).
If the study is well designed and conducted in standardised and controlled manner, i believe that the variability due to design issues, clinical setting and analytical method is very less or negligible.
Regards,
Skar
Complete thread:
- CV from pilot study or reported literature Karmegams 2011-06-16 04:53
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- Credibility of data Helmut 2011-06-16 13:12
- Credibility of dataKarmegams 2011-06-17 11:57
- CV from pilot study or reported literature GSTATS 2011-06-16 20:02
- CV from pilot study or reported literature rajneesh singh 2011-06-17 10:14
- Credibility of data Helmut 2011-06-16 13:12
Ing. Helmut Schütz