Bioequivalence and Bioavailability Forum • Sample size/power for PD BE study 3-way crossover

Sample size/power for PD BE study 3-way crossover [Power / Sample Size]

posted by jdetlor – 2011-04-01 17:52 (5561 d 15:18 ago) – Posting: # 6848
Views: 10,309

Hello all!

In the mean time, would this be a situation where empirical power simulations would be appropriate? Of course initial parameter estimates would be needed.

I could see it becoming quite computationally expensive if bootstraping the final confidence interval is also required (especially the bootstrap BCa CI limits).

J. Detlor

Complete thread:

Sample size/power for PD BE study 3-way crossover Coja66 2011-03-28 14:22
- Sample size/power for PD BE study 3-way crossover Helmut 2011-03-29 14:34
  - Sample size/power for PD BE study 3-way crossover Coja66 2011-03-29 15:31
    - Sample size/power for PD BE study 3-way crossover Dr_Dan 2011-03-30 10:13
      - Sample size/power for PD BE study 3-way crossover Coja66 2011-03-30 11:36
        
        Sample size/power for PD BE study 3-way crossover ElMaestro 2011-03-30 13:48
        
        Off topic (W.H.) Helmut 2011-03-30 13:59
        
        Off topic (W.H.) ElMaestro 2011-03-30 14:54
        
        Off topic (W.H.) Helmut 2011-03-30 15:05
        
        Sample size/power for PD BE study 3-way crossover ElMaestro 2011-03-31 19:55
        
        Sample size/power for PD BE study 3-way crossoverjdetlor 2011-04-01 15:52
        
        Sample size/power for PD BE study 3-way crossover ElMaestro 2011-04-01 16:19
        
        Sample size/power for PD BE study 3-way crossover jdetlor 2011-04-01 16:56
        
        Sample size/power for PD BE study 3-way crossover ElMaestro 2011-04-01 17:14
        
        Sample size/power for PD BE study 3-way crossover jdetlor 2011-04-01 21:51