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RegisterIntra Subject Variability [Power / Sample Size]
Dear HS,
Intrasubject CV is molecule property or its' also affected by formulation property?
For different strengh of same molecule observed with different % CV and repeat study with same strength also observed with different study.
As everybody know that % CV is used to calculate the sample size. So it is always a matter of confusion with % CV take for sample size calculation for next study, i.e., First pilot, recent study or literature based CV.
Kindly provide your valuable inputs with this regards.
Intrasubject CV is molecule property or its' also affected by formulation property?
For different strengh of same molecule observed with different % CV and repeat study with same strength also observed with different study.
As everybody know that % CV is used to calculate the sample size. So it is always a matter of confusion with % CV take for sample size calculation for next study, i.e., First pilot, recent study or literature based CV.
Kindly provide your valuable inputs with this regards.
—
Alps
Alps
Complete thread:
- Intra Subject Variability Phaneendra.K 2011-03-10 12:39
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- Intra Subject Variability Helmut 2011-03-10 12:50
- Intra Subject VariabilityAlpesh Ramani 2011-03-14 09:10
- Intra Subject Variability ElMaestro 2011-03-14 09:19
- Intra Subject VariabilityAlpesh Ramani 2011-03-14 09:10
- Intra Subject Variability Helmut 2011-03-10 12:50
Ing. Helmut Schütz