Bioequivalence and Bioavailability Forum • A posteriori power - No.666

A posteriori power - No.666 [Power / Sample Size]

posted by Marcel – 2011-03-08 15:49 (5584 d 23:01 ago) – Posting: # 6725
Views: 8,347

Dear Helmut,

❝ What were the CVs actually?

❝ • Published one(s)

Typically in mid-40 range (ibandronate)

❝ • Your pilot study

Internal data showed mid-twenties

❝ • Your pivotal study

Our study showed 26.1

❝ ❝ Having read your presentation, I can see why pilot info isn't all that

❝ ❝ great for sample size estimation.

We've attempted sequential design for other products. This option was not really available 4-5 years ago.

Thanks for all your feedback.

Complete thread:

Consumer risk Marcel 2011-03-08 10:56
- Consumer risk ElMaestro 2011-03-08 11:30
  - Consumer risk Marcel 2011-03-08 12:01
    - Consumer risk ElMaestro 2011-03-08 12:13
    - A posteriori power - No.666 Helmut 2011-03-08 12:27
      - A posteriori power - No.666 Marcel 2011-03-08 12:50
        
        A posteriori power - No.666 ElMaestro 2011-03-08 13:06
        A posteriori power - No.666 Helmut 2011-03-08 13:41
        
        A posteriori power - No.666 Marcel 2011-03-08 14:13
        
        A posteriori power - No.666 Helmut 2011-03-08 14:27
        
        A posteriori power - No.666Marcel 2011-03-08 14:49
        
        A posteriori power - No.666 Helmut 2011-03-08 15:03
        
        A posteriori power - No.666 Marcel 2011-03-08 15:28
        
        ... ElMaestro 2011-03-09 23:16

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