Bioequivalence and Bioavailability Forum

A posteriori power - No.666 [Power / Sample Size]

posted by Helmut  – Vienna, Austria, 2011-03-08 13:27 (5586 d 08:27 ago) – Posting: # 6717
Views: 8,393

Dear Marcel!

❝ They have picked up on it and are calling us on it (one CMS only).

The CMS was not by any chance Greece?
They were notoriously asking for a posteriori power in the past.

❝ We have used the standard 5% overall alpha. [...] this is the consumer risk and it has remained the same, correct?

Exactly (see ElMaestro’s posts).

❝ The CMS is taking the position that aposteriori power is not sufficient.

On the contrary – a posteriori power is meaningless. Can you give us the exact wording they have used?

❝ I'm trying to get my head around that.

Maybe one of my presentations helps (slides 26, 40, 47 and the references given).

❝ Seems to me they are confusing consumer risk with producer risk.

Probably – likely.

—
Dif-tor heh smusma 🖖🏼 Довге життя Україна! 
Helmut Schütz


The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes

Complete thread:

• Consumer risk Marcel 2011-03-08 10:56 
  • Consumer risk ElMaestro 2011-03-08 11:30
    • Consumer risk Marcel 2011-03-08 12:01
      • Consumer risk ElMaestro 2011-03-08 12:13
      • A posteriori power - No.666Helmut 2011-03-08 12:27
        • A posteriori power - No.666 Marcel 2011-03-08 12:50
          • A posteriori power - No.666 ElMaestro 2011-03-08 13:06
          • A posteriori power - No.666 Helmut 2011-03-08 13:41
            • A posteriori power - No.666 Marcel 2011-03-08 14:13
              • A posteriori power - No.666 Helmut 2011-03-08 14:27
                • A posteriori power - No.666 Marcel 2011-03-08 14:49
                  • A posteriori power - No.666 Helmut 2011-03-08 15:03
                    • A posteriori power - No.666 Marcel 2011-03-08 15:28
              • ... ElMaestro 2011-03-09 23:16