Three-way vs. four-way replicate design [Power / Sample Size]

posted by Dr Andrew Leary – Ireland, 2010-05-27 18:03 (5875 d 13:39 ago) – Posting: # 5386
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Greetings Helmut et al!

Please excuse the trivial question. I blame medical training, which is short both on mathematics and logic.

If I were to run a four period replicate design study in n=24, this has the statistical power of a standard two-way design in n=48 (along with the added advantage of being able to apply wider limits using SABE).

If I instead choose to run a three period replicate study with equivalent power, my understanding this should include n=36. However, in this case the T/R comparison involves 36 sets of data, while the 4-period design involves 48 T/R comparisons. Surely that gives the 4-period design an advantage?

Where has my logic gone wrong?

Kind regards

Andrew

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