Bioequivalence and Bioavailability Forum • Intra subject CV consideration

Intra subject CV consideration [Power / Sample Size]

posted by Sriraj – India, 2010-04-14 11:30 (5918 d 20:35 ago) – Posting: # 5117
Views: 6,823

Dear Rasheed,

I am getting confused with this.
My question is, suppose if we have CV% where Drug A with x dosage administered in tablet and capsule formulations from Study-1, and now if we are conducting a study (Study-2) with different design and with different dosage, say Study-2 is of food effect study with Drug A with y-dosage then can we use the CV% information from study-1 to evaluate the sample size for Study-2.

Thank you,
SriKanth

Complete thread:

Intra subject CV consideration Sriraj 2010-04-12 09:39
- Intra subject CV consideration rasheed 2010-04-13 06:21
  - Intra subject CV consideration Sriraj 2010-04-13 09:31
    - Intra subject CV consideration rasheed 2010-04-13 11:19
      - No full quote ! Ohlbe 2010-04-13 12:05
        
        No full quote ! rasheed 2010-04-13 12:25
      - Intra subject CV considerationSriraj 2010-04-14 09:30
        
        Intra subject CV consideration Dr_Dan 2010-04-14 10:24
        
        Intra subject CV consideration Sriraj 2010-04-14 10:40
        
        Intra subject CV consideration rasheed 2010-04-14 12:35
        Intra subject CV consideration Ohlbe 2010-04-14 15:32
- Intra subject CV consideration statistician 2010-09-27 14:51