AUCinf » AUCt?? [Power / Sample Size]

posted by Helmut Homepage – Vienna, Austria, 2009-12-19 13:40 (6031 d 03:25 ago) – Posting: # 4508
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Dear Yuvraj,

why don’t you answer our questions first?

Your calculation is based on the flawed assumption that in the pivotal study the PE and CV will be exactly like in the pilot – do you really believe in that?
Your sample size would be 1290 if the PE 116.66->116.67. Do you want to set a new world record in BE? Remember that based on your calculations human subjects will be treated – this is not a game to play with numbers.

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