Bioequivalence and Bioavailability Forum

Power with a Danish twist [Power / Sample Size]

posted by d_labes  – Berlin, Germany, 2009-05-08 18:06 (6251 d 14:21 ago) – Posting: # 3662
Views: 12,171

Dear Helmut, dear ElMaestro!

❝ ❝ *: What's the real power at CV=65%, R/T=95%, 38 sbj (19 in each seq)??

❝

❝ Good question. I think we are pushing software to the limits, i.e.,

❝ running into troubles of getting a rasonable value of the noncentral

❝ t-distribution (numeric precision,...).

❝ Fartssie comes up with -0.0278 (!), StudySize 2.01 simply gives up (-),

❝ and my R-code [...]

❝ gets stuck at 40 subjects (power 0.454%)...

My Extreme computing SASophylistic gives
Power = 4.50940122 %
As you know precise up to the last digit .

Simulated with 8000 resamplings I come up with 4.6% (normal BE test).

Complete thread:

• Power with a Danish twist ElMaestro 2009-05-05 19:49 
  • population parameter martin 2009-05-05 21:32
    • population parameter ElMaestro 2009-05-05 21:48
      • population parameter martin 2009-05-05 22:59
  • Wrong Question Answer in Danish d_labes 2009-05-08 09:49
    • Danish numbers d_labes 2009-05-08 15:53
      • Danish numbers ElMaestro 2009-05-08 20:19
  • Power with a Danish twist Helmut 2009-05-08 13:23
    • Power with a Danish twistd_labes 2009-05-08 16:06
      • Power with a Danish twist Helmut 2009-05-08 16:15
    • Power with a Danish twist ElMaestro 2009-05-08 19:40
  • Power with a Danish twist Helmut 2009-05-08 16:56
    • Power with a Danish twist ElMaestro 2009-05-08 19:17