Sample size for multiple dose study [Power / Sample Size]

posted by Ravi  – India, 2008-11-27 13:59 (6417 d 11:20 ago) – Posting: # 2820
Views: 4,184

Dear HS

❝ ❝ Yes. But don't forget to allow for the usual safety margins (prediction

❝ from a small pilot study [T/R and CV% are uncertain]


We have conducted the pilot study on 24 subjects and study design was 3 x 6 crossover. Now can we predict sample size from estimates of this studies for a 2 x 2 crossover Multiple dose study.
—
Thanks & Regards
Ravi Pandey

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