Bioequivalence and Bioavailability Forum • Sample size, ratio, CV ↔ power

Sample size, ratio, CV ↔ power [Power / Sample Size]

posted by BEQool – 2025-01-31 14:12 (84 d 02:10 ago) – Posting: # 24355
Views: 1,402

Hello!

❝ A significant treatment effect will show up in all studies where the confidence interval does not include unity.

Is this always true? Or better, in which cases this isnt true? What could be the reason? Namely I saw a case with lower limit of 90% CI of 102.3% and p-value for treatment effect of 0.055.
So based on 90% CI, treatment effect should be significant but here it isnt :confused:

BEQool

Complete thread:

Significance The Outlaw Torn 2012-11-20 07:56
- Significance ElMaestro 2012-11-20 08:17
  - Significance The Outlaw Torn 2012-11-20 08:55
    - Quality vs. Clinical ElMaestro 2012-11-20 09:04
- Sample size? Helmut 2012-11-20 20:10
  - Sample size? The Outlaw Torn 2012-11-21 07:52
  - Sample size? The Outlaw Torn 2012-11-22 10:55
    - Sample size, ratio, CV ↔ power Helmut 2012-11-22 13:35
      - Sample size, ratio, CV ↔ power The Outlaw Torn 2012-11-23 14:47
      - Sample size, ratio, CV ↔ powerBEQool 2025-01-31 13:12
        
        TOST != treatment effect mittyri 2025-02-20 13:13
        Sample size, ratio, CV ↔ power zizou 2025-02-21 13:40
        
        Not vice versa mittyri 2025-02-22 21:08
        
        Not vice versa? zizou 2025-02-24 11:02
        
        Not vice versa? mittyri 2025-02-25 06:12
- Sample size calculation using Marzo and Balant method kumarnaidu 2013-01-31 07:48
  - Marzo / Balant formula d_labes 2013-01-31 10:05
    - Marzo / Balant formula kumarnaidu 2013-01-31 10:54
      - Marzo / Balant formula kumarnaidu 2013-02-04 05:48
        
        Marzo / Balant formula for parallel groups d_labes 2013-02-04 08:44