Log in
RegisterWithin subject variability [Power / Sample Size]
Dear all,
I am exploring the hypothesis to use the within subject variability obtained on conventional 2 way crossover bioequivalence study and apply it in scale average bioequivalence as described for a replicated design used for HVD or NTI.
I know that within subject variability of reference would be necessary, but I have no replicated design. My doubt is if these values have any relation somehow like, for instance, the first one is larger than the second one or there is no relationship at all?
Kind Regards
MaggieSantos
Edit: Category changed; see also this post #1. [Helmut]
I am exploring the hypothesis to use the within subject variability obtained on conventional 2 way crossover bioequivalence study and apply it in scale average bioequivalence as described for a replicated design used for HVD or NTI.
I know that within subject variability of reference would be necessary, but I have no replicated design. My doubt is if these values have any relation somehow like, for instance, the first one is larger than the second one or there is no relationship at all?
Kind Regards
MaggieSantos
Edit: Category changed; see also this post #1. [Helmut]
Complete thread:
- Within subject variabilityMaggieSantos 2018-03-15 22:51
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- CVw pooled from CVwT and CVwR Helmut 2018-03-16 12:56
Ing. Helmut Schütz