Bioequivalence and Bioavailability Forum

111.11 for NTIDs [Power / Sample Size]

posted by Astea – Russia, 2018-02-05 20:27 (3052 d 20:59 ago) – Posting: # 18358
Views: 26,038

Dear Helmut!

❝ Where did you find that?

I have to apologize - it turned out that I reffered to the draft version . In two years the mistape was corrected (or someone improved its rounding skills :)

❝ I’m not willing to accept 111.11%. Heck, with an acceptable ∆ of 10% we get \(100(1-\Delta)^{-1}=111.1\dot{1}\) – nothing else! I will not forget my second-grade math only cause it’s claimed ex cathedra by the oracle. Had to swallow already rounding of the CI. Double rounding? Gimme a break!

Then why do we use 80,00? "Because in the former case the numbers look nicer and are easier to remember
Of course 111.00 is nonsense and should be forgotten.

Complete thread:

• Sample size for 4-period 4-sequence crossover BE study Bryony Simmons 2018-02-01 12:16 
  • function sampleN.TOST of package PowerTOST Helmut 2018-02-01 13:01
    • Alpha adjustment in higher order crossover d_labes 2018-02-01 14:01
      • Deficiencies Helmut 2018-02-01 15:48
        • Deficiencies nobody 2018-02-01 17:10
        • Deficiencies d_labes 2018-02-01 18:57
          • Deficiencies Relaxation 2018-02-02 11:12
            • Deficiencies nobody 2018-02-02 12:49
            • Deficiencies Helmut 2018-02-02 16:14
              • Deficiencies Relaxation 2018-02-02 19:41
                • alpha... where is omega? Astea 2018-02-02 21:45
                  • α and no ω Helmut 2018-02-02 23:39
                    • TIE for NTIDs d_labes 2018-02-04 12:40
                      • TIE for NTIDs Astea 2018-02-04 20:04
                        • TIE for NTIDs Helmut 2018-02-05 01:01
                          • TIE for NTIDs d_labes 2018-02-05 16:40
                            • TIE for NTIDs Helmut 2018-02-05 17:49
                              • TIE for NTIDs d_labes 2018-02-05 22:17
                                • TIE for NTIDs Helmut 2018-02-06 12:34
                        • TIE for NTIDs d_labes 2018-02-05 16:35
                          • bow TIE for NTIDs Astea 2018-02-05 17:52
                            • bow TIE for NTIDs Helmut 2018-02-05 18:10
                              • 111.11 for NTIDsAstea 2018-02-05 19:27
                                • 111.11 for NTIDs Helmut 2018-02-06 00:12
                            • bow TIE for NTIDs d_labes 2018-02-05 22:33