The reasons not to pool [Power / Sample Size]

posted by Astea – Russia, 2016-08-26 22:40 (3585 d 10:44 ago) – Posting: # 16597
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Dear all!

As I understand, pooling CV is a part of metha-analysis. In its turn meta-analysis conceals many suprises, Simpson's paradox as example. The question is how to make sure of homogenity of pooling data? What can be the reasons to throw out some outlier data, excluding Gut feeling? Can we pool data from studies with different dosage or studies with different formulations? How do the strength of the dosage affects variability?

"Being in minority, even a minority of one, did not make you mad"

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