Bioequivalence and Bioavailability Forum • Maximum CV might be misleading

Maximum CV might be misleading [Power / Sample Size]

posted by BE-proff – 2016-08-26 12:41 (3581 d 17:18 ago) – Posting: # 16579
Views: 14,926

Hi Helmut,

Many thanks for your detailed explanation!
Pooled CV looks really interesting :)

One more question

Let's say I have results of 3 studies (imagined):
n=24, CV=0.16
n=36, CV=0.28
n=18, CV=0.14

How to write R-code in this case to calculate CV pooled?

Thank you.

Proff.

Complete thread:

Why do we need pooled CV? BE-proff 2016-08-24 08:48
- Maximum CV might be misleading Helmut 2016-08-24 12:07
  - Maximum CV might be misleadingBE-proff 2016-08-26 10:41
    - Pooling – example Helmut 2016-08-26 11:34
      - Pooling – example BE-proff 2016-12-28 14:37
        
        in my protocols… Helmut 2016-12-29 12:27
- Why do we need pooled CV? ElMaestro 2016-08-24 13:03
  - Yessir! Common sense! Helmut 2016-08-24 13:53
    - Common sense weighting before pooling mittyri 2016-08-24 15:13
  - Gut feeling is the answer! DavidManteigas 2016-08-25 11:09
    - The reasons not to pool Astea 2016-08-26 20:40
      - The reasons not to pool mittyri 2016-08-28 22:05
      - Know your drug/formulation! Helmut 2016-08-29 11:56