parallel design [Power / Sample Size]

posted by mathews – 2008-02-14 13:10 (6698 d 20:06 ago) – Posting: # 1612
Views: 6,936

Dear HS,

One more doubt. In the paper

S-C Chow and H Wang
On Sample Size Calculation in Bioequivalence Trials
J Pharmacokin Pharmacodyn 28/2, 2001


they are given sample sizes for parallel design using logtransformed data in Table1.

In that table what is the sigma% represents?..Is it the total CV?

So if I know the Cmax or AUC value (mean ± s.d). Then is it correct if I calculate the total CV as (s.d/mean)*100.? Is it correct ?.


regards

Matz.

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