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RegisterSample size for replicate design [Power / Sample Size]
Dear collegues,
This query appears novice but I am not a statistician. For a HVD, I have done a 4-way pilot and the ISCV's are >30% true to the drug nature. Please let me know if I need to carry a pivotal again with a replicate design or a 2 way cross-over would do.
Also please let me know if the sample size calculation from SAS is valid for 4 way cross-over. If not how do I calculate the sample size for a replicate design based on the ISCV's from a 4 way pilot.
This query appears novice but I am not a statistician. For a HVD, I have done a 4-way pilot and the ISCV's are >30% true to the drug nature. Please let me know if I need to carry a pivotal again with a replicate design or a 2 way cross-over would do.
Also please let me know if the sample size calculation from SAS is valid for 4 way cross-over. If not how do I calculate the sample size for a replicate design based on the ISCV's from a 4 way pilot.
Complete thread:
- Sample size for replicate designmichel 2008-02-08 01:57
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Ing. Helmut Schütz