PE at border of the AR: power ≤0.05! [Power / Sample Size]

posted by zizou – Plzeň, Czech Republic, 2016-01-24 23:12 (3808 d 19:24 ago) – Posting: # 15850
Views: 13,407

❝ At GMR 0.8 and sample sizes <49 power starts to drop below 0.05. With n=12 it is only 0.0337.


Very nice and interesting 3D figure.
Nevertheless in practice power is almost equal to 0.05 at GMR 0.8000 (if you replace axis "sample size" by "CV" in the figure and the points (for each CV) will be calculated as for minimum required sample size, the curve with power 0.05 (almost straight line) will be approximately at GMR 0.80).
So alpha could be seen as less than 0.05 (with two decimals accuracy) only in pilot studies or in really underpowered studies. (If I am not mistaken.)

❝ Seems that I’ve forgotten my own “Don’t panic!” slide. In the dark ages I used to write in my reports “α ≤0.05” and “≥90% CI” and earned questions.


To the slide, the figure is for classical 2x2 design? It seems strange to me, especially curve alpha=0.0500, which is raising and I'm not getting why it's descreasing with n>56. Try recalculation at n=60, CV=35% (last minor tick) ... with GMR 0.80, the power will be 0.0500 (so this point should be under the curve 0.0500 and not above) or am I wrong somewhere?
Maybe I am just not understanding the slide without the comments presented in Barcelona.

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