Post hoc Power [Power / Sample Size]

posted by ElMaestro  – Denmark, 2016-01-08 16:07 (3823 d 18:24 ago) – Posting: # 15805
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Hi Jay,

❝ As per discussions previous posts, the post of power is not taken into much consideration.

❝ But when the post hoc power of AUCt and AUCinf is observed around 90-100% while the posthoc power of Cmax is less than 20%, then what would be the probable reason for the same.


First of all, I think you should mention how you calculate post-hoc power. Do you use GMR=0.95, GMR=1.0 or observed?
Anyways, low post-hoc power could be due to deviating GMR (for the case you use the observed GMR; this is likely a product failure) or it could be due to high variability, or both.

If you have a situation with deviating Cmax point estimate but OK AUCt point estimate, then you are facing a challenge.

Having said all, I must admit I am also in the camp of people who think post-hoc power is either rubbish or of very limited value.

Pass or fail!
ElMaestro

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