Bioequivalence and Bioavailability Forum

❝ From my point of view, this may simply be a misleading finding due to chance, because, staying in that example, conducting three studies at a power of 80% will result in a fifty-fifty chance to have all of them being successful (0.8^3). By implication, it might even be reasonable to "overpower" each single study in order to end with an "overall power" of 80% (0.93^3 is roughly 80%).