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RegisterWhy not? [Power / Sample Size]
Dear Jay,
If you believe in that CV's, i.e. all was OK with the study conduct:
Why not?
There is not theoretical bound in the CV, beside it has to be > zero.
❝ In pilot study results of a modified release molecule, the CV obtained for AUC5-t is 114% and the T/R is around 88%.
❝ Can one use CV for more than 100% i.e. 114% in above case for the calculation of pivotal sample size.
If you believe in that CV's, i.e. all was OK with the study conduct:
Why not?
There is not theoretical bound in the CV, beside it has to be > zero.
—
Regards,
Detlew
Regards,
Detlew
Complete thread:
- Sample size with CV more than 100% Jay 2015-11-02 10:47
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- Why not?d_labes 2015-11-02 11:08
- Why not? Jay 2015-11-02 11:29
- Sample size for HVD's d_labes 2015-11-02 13:06
- EMA: MR – ABEL for partial AUCs Helmut 2015-11-02 14:35
- EMA: MR – ABEL for partial AUCs d_labes 2015-11-02 14:48
- EMA: MR – ABEL for partial AUCs Helmut 2015-11-02 14:35
- Sample size for HVD's d_labes 2015-11-02 13:06
- Why not? Jay 2015-11-02 11:29
- Why not?d_labes 2015-11-02 11:08
Ing. Helmut Schütz