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RegisterThe power of post hoc power [Power / Sample Size]
Good day to all,
Another return to post hoc power analysis to raise Helmut's blood pressure. Ha!
Is post hoc power analysis also useless for therapeutic equivalence trials (non-inferiority, two arm, active-controlled, parallel group) intended to demonstrate the IOP-lowering efficacy of a generic anti-glaucoma medication versus the originator?
My first thought is that, yeah, it's the same principle as with standard bioequivalence, but since the confidence intervals are measured in mm Hg, I become uncertain as a non-statistician.
Questions are being raised that the sample size may have been inadequate.
Any comment by anyone is appreciated and thank you in advance.
Outlaw Torn
Edit: Category changed. [Helmut]
Another return to post hoc power analysis to raise Helmut's blood pressure. Ha!
Is post hoc power analysis also useless for therapeutic equivalence trials (non-inferiority, two arm, active-controlled, parallel group) intended to demonstrate the IOP-lowering efficacy of a generic anti-glaucoma medication versus the originator?
My first thought is that, yeah, it's the same principle as with standard bioequivalence, but since the confidence intervals are measured in mm Hg, I become uncertain as a non-statistician.
Questions are being raised that the sample size may have been inadequate.
Any comment by anyone is appreciated and thank you in advance.
Outlaw Torn
Edit: Category changed. [Helmut]
Complete thread:
- The power of post hoc powerThe Outlaw Torn 2015-05-13 12:49
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- The power of post hoc power ElMaestro 2015-05-13 17:53
- Ad hoc power d_labes 2015-05-13 20:18
- Ad hoc power The Outlaw Torn 2015-05-14 11:38
- Ad hoc power The Outlaw Torn 2015-06-15 11:20
- Hypotheses in non-inferiority trials mittyri 2015-06-16 21:52
- Hypotheses in non-inferiority trials The Outlaw Torn 2015-06-17 11:35
- Hypotheses in non-inferiority trials d_labes 2015-06-18 10:17
- Hypotheses in non-inferiority trials The Outlaw Torn 2015-06-22 10:23
- Hypotheses in non-inferiority trials arjunroy 2015-06-29 08:24
- Hypotheses in non-inferiority trials The Outlaw Torn 2015-06-22 10:23
- Hypotheses in non-inferiority trials d_labes 2015-06-18 10:17
- Hypotheses in non-inferiority trials The Outlaw Torn 2015-06-17 11:35
- Hypotheses in non-inferiority trials mittyri 2015-06-16 21:52
- Ad hoc power The Outlaw Torn 2015-06-15 11:20
- Ad hoc power The Outlaw Torn 2015-05-14 11:38
- Ad hoc power d_labes 2015-05-13 20:18
- The power of post hoc power ElMaestro 2015-05-13 17:53
Ing. Helmut Schütz