Bioequivalence and Bioavailability Forum

GMR ∉ AR ⇒ power <5% [Power / Sample Size]

posted by Helmut  – Vienna, Austria, 2015-02-24 02:33 (4137 d 13:22 ago) – Posting: # 14494
Views: 17,693

Hi ElMaestro,

❝ Completely correct. Crap is the proper diplomatic term. […] Common sense seems to be in short supply these days.

Rule of thumb: GMR at acceptance limit, sample size = ∞, vari­ance = 0, power = type I error ≤ 5%.

—
Dif-tor heh smusma 🖖🏼 Довге життя Україна! 
Helmut Schütz


The quality of responses received is directly proportional to the quality of the question asked. 🚮
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Complete thread:

• minimum number of subject in bioequivalence study khaoula 2014-09-27 11:14 
  • minimum number of subject in bioequivalence study ElMaestro 2014-09-27 11:26
    • minimum number of subject in bioequivalence study khaoula 2014-09-27 23:49
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        • “Overpowered” studies due to GLs khaoula 2014-09-28 22:36
          • “Overpowered” studies due to GLs Helmut 2014-09-29 03:51
        • Scientific Validation for the Sample Size Formula mreyes 2014-11-07 19:47
          • Basic maths Helmut 2014-11-07 20:09
            • Basic maths mreyes 2014-11-07 20:47
          • Reference for CI ⇒ MSE Helmut 2014-12-14 01:51
            • Reference for CI ⇒ MSE mreyes 2015-02-19 19:50
              • Failed study: power <80%! Helmut 2015-02-20 19:09
                • Failed study: power <80%! mreyes 2015-02-23 17:07
                  • Reported 99.98%, correct 1.4% Helmut 2015-02-23 17:38
                    • Reported 99.98%, correct 1.4% ElMaestro 2015-02-23 17:51
                      • GMR ∉ AR ⇒ power <5%Helmut 2015-02-24 01:33
                        • GMR ∉ AR ⇒ power <5% mreyes 2015-02-24 17:34