Bioequivalence and Bioavailability Forum

A wee little hole in the coconut [Power / Sample Size]

posted by Helmut  – Vienna, Austria, 2014-10-04 21:23 (4277 d 09:38 ago) – Posting: # 13649
Views: 15,096

Dear Apprentice of power estimations,

❝ Anyone got the Philips paper from 1990?

I’ll send you a scan. Note that the paper deals with untransformed data (AR 0.80–1.20). More relevant the one by Diletti et al.*

❝ Using the world's best package for power calculation known as power.TOST:

❝

❝ cv=sqrt(exp(0.1003) - 1.0)

Another guy not reading the man-pages.
Try this goodie:
sampleN.TOST(CV=mse2CV(0.1003), theta0=1.1, targetpower=.95)

---

• Diletti E, Hauschke D, and VW Steinijans
  Sample size determination for bioequivalence assessment by means of con­fi­dence intervals
  Int J Clin Pharm Ther Toxicol 29(1), 1–8 (1991)
  PMID: 2004861

—
Dif-tor heh smusma 🖖🏼 Довге життя Україна! 
Helmut Schütz


The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes

Complete thread:

• Proc power ElMaestro 2014-09-30 11:23 
  • Proc power d_labes 2014-10-01 09:26
  • Proc power jag009 2014-10-01 20:55
    • screen shot ElMaestro 2014-10-01 21:02
      • Paired design d_labes 2014-10-02 13:00
        • Paired design ElMaestro 2014-10-02 13:33
          • Paired design Helmut 2014-10-02 13:43
            • Paired design nobody 2014-10-02 14:00
            • Paired design ElMaestro 2014-10-02 14:25
              • A wee little hole in the coconut ElMaestro 2014-10-04 18:13
                • A wee little hole in the coconutHelmut 2014-10-04 19:23
          • Paired design Ben 2014-10-05 10:43
            • Paired design ElMaestro 2014-10-05 14:01