Bioequivalence and Bioavailability Forum • GMR and variability

GMR and variability [Power / Sample Size]

posted by d_labes – Berlin, Germany, 2014-05-18 16:40 (4416 d 19:01 ago) – Posting: # 12964
Views: 7,288

Dear ElMaestro!

❝ ... That variance is conditional on and associated with the GMR point estimate. It is the treatment effects (the GMR so to say) that determines the CV, not the other way around ...

I think you err here. AFAIK the treatment effect (GMR) and the residual variance (CV) are independent.

—
Regards,

Detlew

Complete thread:

Sample size calculation based on T/R ratio Tina 2014-05-16 11:38
- Sample size calculation based on T/R ratio ElMaestro 2014-05-16 13:34
- Sample size calculation based on T/R ratio Ohlbe 2014-05-16 14:27
  - Sample size calculation based on T/R ratio Tina 2014-05-16 17:39
    - Sample size calculation based on T/R ratio ElMaestro 2014-05-16 18:31
      - GMR and variabilityd_labes 2014-05-18 14:40