Bioequivalence and Bioavailability Forum • Sample size calculation based on T/R ratio

Sample size calculation based on T/R ratio [Power / Sample Size]

posted by Tina – India, 2014-05-16 19:39 (4426 d 10:51 ago) – Posting: # 12962
Views: 7,347

Dear ElMaestro and Ohlbe,

Thanks for the clear explanation.

I wouldn't take the risk of 95-105 considering the possibility of the final value to go outside the assumption.

For Potvin B method for calculation, should the expectation also be 90 to 110?
Stage II sample size is calculated when power is less than 80%. Why do we say that the study has failed at the completion of stage I if the power is more than or equal to 80%?

Kind regards,
Tina

Complete thread:

Sample size calculation based on T/R ratio Tina 2014-05-16 11:38
- Sample size calculation based on T/R ratio ElMaestro 2014-05-16 13:34
- Sample size calculation based on T/R ratio Ohlbe 2014-05-16 14:27
  - Sample size calculation based on T/R ratioTina 2014-05-16 17:39
    - Sample size calculation based on T/R ratio ElMaestro 2014-05-16 18:31
      - GMR and variability d_labes 2014-05-18 14:40