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RegisterNon-parametric tests [Power / Sample Size]
posted by Helmut 
– Vienna, Austria, 2007-11-11 18:59 (6801 d 20:36 ago) – Posting: # 1295
Views: 5,635
Dear Snigdhasantra!
In the context of bioequivalence, which kind of PK metric are you testing?
The Z test is parametric (based on the normal distribution).
For sample size estimation of nonparametric tests you have two options:
Chow, S-C, Shao J, Wang H. Sample Size Calculations In Clinical Research. Marcel Dekker, New York pp 277-292 (2003)
❝ I would like to know if we can calculate sample size in case of a study in which only non-parametric tests (chi square test and Z test) will be applied.
In the context of bioequivalence, which kind of PK metric are you testing?
The Z test is parametric (based on the normal distribution).
For sample size estimation of nonparametric tests you have two options:
- applying asymptotic normal approximations, or
- bootstrapping.
Chow, S-C, Shao J, Wang H. Sample Size Calculations In Clinical Research. Marcel Dekker, New York pp 277-292 (2003)
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Dif-tor heh smusma 🖖🏼 Довге життя Україна!
Helmut Schütz
The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes
Complete thread:
- Non-parametric tests Snigdhasantra 2007-11-11 15:37
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- Non-parametric testsHelmut 2007-11-11 17:59
Ing. Helmut Schütz