Justification on Sample size… [Power / Sample Size]

posted by Tushar.g  – India, 2013-12-24 15:04 (4568 d 13:42 ago) – Posting: # 12102
Views: 4,809

Hi all,

For Sample size calculation, we normally select higher intra CV of primary parameter (Cmax or AUC). Our IEC ask for scientific justification (literature) for why to choose higher Intra CV parameter for sample size calculation only. Kindly suggest.
Thanks in advance & happy holidays.

Regards,
Tushar

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