Bioequivalence and Bioavailability Forum

Difference between Cminss and Ctauss? tekwani.sunil 2014-12-03 07:10
- Difference between Cminss and Ctauss? Helmut 2014-12-03 13:11
  - Difference between Cminss and Ctauss? tekwani.sunil 2014-12-04 05:53
    - Difference between Cminss and Ctauss? Helmut 2014-12-04 14:21

Ctau at steady state calculation RK 2014-07-03 11:37
- Estimated Cτ, if possible Helmut 2014-07-04 00:19

Regarding the Cτ,ss (Ctau at steady state) calculation murthynaidu 2014-06-20 14:46
- What’s stated in the protocol? Helmut 2014-06-20 15:20
  - What’s stated in the protocol? murthynaidu 2014-06-20 15:48
    - Avoid ambiguities… Helmut 2014-06-20 16:17

how to get study state Cmax DrBABU 2014-05-13 10:35
- how to get study state Cmax Helmut 2014-05-13 10:43
  - “study state conditions”? DrBABU 2014-05-13 13:12
    - I beg your pardon… Helmut 2014-05-13 13:27
      - I beg your pardon… jag009 2014-05-14 16:28

Calculation of AUCt yckim 2007-11-27 02:46
- Calculation of AUCt, AUCall, AUCinf... Helmut 2007-11-27 22:02
  - Calculation of AUCt, AUCall, AUCinf... yckim 2007-11-28 02:44
    - Calculation of AUCt, AUCall, AUCinf... Helmut 2007-11-28 03:49
      - Calculation of AUCt, AUCall, AUCinf... jmlee 2008-10-10 08:29
        
        Calculation of AUCt, AUCall, AUCinf... Helmut 2008-10-10 17:48
        Calculation of AUCt, AUCall, AUCinf... mittyri 2014-03-19 19:15
        
        Errors happen d_labes 2014-03-20 08:26
        
        Errors happen fno 2014-03-20 11:03
  - Calculation of AUCt, AUCall, AUCinf... Ohlbe 2007-11-28 10:37
    - Calculation of AUCt, AUCall, AUCinf... Helmut 2007-11-28 12:28
      - References Helmut 2007-11-28 17:58

Actual time for PK analysis ratnakar1811 2013-10-07 08:07
- estimated AUC72 Helmut 2013-10-07 13:36
  - estimated AUC72 ratnakar1811 2013-10-08 08:20
    - estimated AUC72 sam 2013-10-08 13:15
    - estimated AUC72 Helmut 2013-10-08 13:51
      - estimated AUC72 ratnakar1811 2013-10-10 11:30
        
        estimated AUC72 jag009 2013-10-13 21:17
        
        estimated AUC72 ratnakar1811 2013-10-15 06:23
        
        estimated AUC72 Dr_Dan 2013-10-15 12:24
        estimated AUC72 jag009 2013-10-15 21:53
        
        estimated AUC72 ratnakar1811 2013-10-17 09:34

Urine concentration data analysis RK 2013-08-29 14:27
- Cumulative amount Helmut 2013-08-29 14:52

Russian Guidance – PK Data assay Karthikeyan 2013-08-27 13:54
- Plateau-time etc. Helmut 2013-08-27 14:44
- Russian Guidance – PK Data assay Dr_Dan 2013-08-27 15:39
  - Russian Guidance – PK Data assay Helmut 2013-08-27 16:31
    - t75% Dr_Dan 2013-08-27 16:56
      - t75% Helmut 2013-08-27 17:37
        
        t75% mittyri 2013-08-28 09:51
        
        t75% (reporting only?) Helmut 2013-08-28 14:32
  - Partial AUC? Helmut 2013-08-28 17:42
    - Partial AUC? Dr_Dan 2013-08-28 21:08
      - Partial AUC? Karthikeyan 2013-08-29 14:04

Failing BE study due to AUCinf jag009 2013-06-19 17:44
- AUC∞ = lousy metric Helmut 2013-06-19 18:15
  - AUC∞ = lousy metric jag009 2013-06-19 19:35
  - AUC∞ = lousy metric jag009 2013-06-19 21:20
    - AUC∞ = lousy metric Helmut 2013-06-20 17:29
      - AUC∞ = lousy metric jag009 2013-06-20 20:32
- Failing BE study due to AUCinf ElMaestro 2013-06-19 18:48
  - Failing BE study due to AUCinf jag009 2013-06-19 19:41
    - BS Helmut 2013-06-20 17:59
      - BS jag009 2013-06-20 20:35

handling of missing data gracehung 2013-05-20 07:35
- Lin-up/log-down trapezoidal avoids most trouble Helmut 2013-05-20 14:22
  - Lin-up/log-down trapezoidal avoids most trouble yjlee168 2013-05-22 08:25
    - Multiple peaks: fallback to linear trapezoidal Helmut 2013-05-22 20:25
      - Multiple peaks: fallback to linear trapezoidal yjlee168 2013-05-22 21:57
        
        No interpolation Helmut 2013-05-22 23:25
        
        No interpolation yjlee168 2013-05-23 11:43
        
        Spaghetti & other pasta Helmut 2013-05-23 15:15
        
        Spaghetti & other pasta yjlee168 2013-05-23 20:47
        
        Spaghetti & other pasta Helmut 2013-05-23 21:29
        
        Spaghetti & other pasta yjlee168 2013-05-23 22:46
        
        Spaghetti & other pasta Helmut 2013-05-24 01:24
        
        Spaghetti & other pasta yjlee168 2013-05-24 09:17
        
        No interpolation Ken Peh 2013-05-30 19:55
        
        Different algos! Helmut 2013-05-30 22:38
        
        Different algos! Ken Peh 2013-06-03 17:52
        
        Calculate what? Helmut 2013-06-03 18:11
    - Lin-up/log-down trapezoidal example Helmut 2013-05-25 15:09
      - Lin-up/log-down trapezoidal example yjlee168 2013-05-25 19:45
- handling of missing data Ohlbe 2013-05-20 21:45
  - Sorry Helmut 2013-05-21 13:53
    - Sorry gracehung 2013-05-23 01:06
      - Uncertain time point Helmut 2013-05-23 01:35

Long t½ drugs jag009 2012-12-05 16:04
- Long t½ drugs Helmut 2012-12-05 19:41
  - Long t½ drugs jag009 2012-12-05 22:04

Difference between Cminss and Ctrough rana 2012-11-23 14:49
- Difference between Cminss and Ctrough drgunasakaran1 2012-11-23 15:10
- EMA’s odd terminology… Helmut 2012-11-23 15:15

Adderall XR: pAUCs Helmut 2012-10-01 23:50
- Adderall XR: pAUCs jag009 2012-10-02 15:10
  - Guidance Sep 2012 Helmut 2012-10-02 15:32
    - Guidance Sep 2012 jag009 2012-10-02 16:44

Cmin calculation steady state VG 2012-07-30 07:02
- Cmin calculation steady state RVR 2012-07-30 11:51
  - Cmin calculation steady state VG 2012-07-31 11:14
  - Cmin - search, search, search and once more: search d_labes 2012-07-31 13:33

Methods for calculation of half lives d_labes 2008-02-01 14:58
- Methods for calculation of half lives Helmut 2008-02-01 16:59
  - Methods for calculation of half lives Ohlbe 2008-02-02 23:00
    - Minimum AIC?! Helmut 2008-02-03 13:49
      - G (Kinetica) = R²adj (WinNonlin) Helmut 2008-02-04 01:12
  - Methods for calculation of half lives d_labes 2008-02-04 16:43
    - MAIC and beyond... Helmut 2008-02-04 17:49
- TTT method Helmut 2008-05-10 13:56
  - TTT method d_labes 2008-05-16 09:12
    - TTT method Helmut 2008-05-16 17:21
      - TTT method d_labes 2008-05-23 15:43
        
        TTT method hiren379 2012-07-11 11:11
        
        TTT method Ohlbe 2012-07-11 11:37
        
        TTT method hiren379 2012-07-11 11:44
        
        TTT method Ohlbe 2012-07-11 12:16
        
        TTT method hiren379 2012-07-11 12:53
        
        Eyeball-PK Helmut 2012-07-11 14:37
        
        Eyeball-PK hiren379 2012-07-11 15:28
        
        Eyeball-PK Helmut 2012-07-11 15:47
        
        Eyeball-PK hiren379 2012-07-11 16:24

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