Bioequivalence and Bioavailability Forum

Metrics for absorption Helmut 2019-04-15 12:08
- Metrics for absorption nobody 2019-04-15 12:15
  - Metrics for absorption ElMaestro 2019-04-15 12:23
    - Metrics for absorption nobody 2019-04-15 12:39
  - Metrics for absorption Helmut 2019-04-15 13:02
    - Metrics for absorption nobody 2019-04-15 13:48
      - Metrics for absorption Helmut 2019-04-15 19:31
        
        Metrics for absorption nobody 2019-04-16 09:34
        
        Metrics for absorption nobody 2019-04-16 15:15
        
        Metrics for absorption Helmut 2019-04-16 17:01
        
        Metrics for absorption nobody 2019-04-17 11:15
        
        Simulation framework mittyri 2019-04-17 01:21
        
        Simulation framework Helmut 2019-04-17 13:31
        
        Conclusion mittyri 2019-04-17 15:42
        
        Conclusion & beyond Helmut 2019-04-17 17:05

AUC0-tau at steady state BNR 2016-03-31 22:46
- AUC0-tau at steady state jag009 2016-03-31 23:05
  - AUC0-tau at steady state BNR 2016-03-31 23:43
    - RTFM Helmut 2016-04-01 00:59
      - RTFM BNR 2016-04-01 02:05
      - AUC0-τ estimation with time deviations Astea 2019-02-10 16:38
        
        AUC0-τ estimation with time deviations Helmut 2019-02-10 19:32
        
        Cτ for lin and lin-up/log-down Astea 2019-02-10 20:50
        
        Cτ by lin-/lin, lin-up/log-down, and λz Helmut 2019-02-11 01:45
        
        inter- vs extra- Astea 2019-02-11 19:46
        
        inter- vs extra- Helmut 2019-02-12 02:20
        No rule fits all mittyri 2019-02-14 12:55
        
        one size fits all vs goal posts Astea 2019-02-16 08:33
        
        one size fits all vs goal posts ElMaestro 2019-02-16 13:33
        
        Bias etc. Helmut 2019-02-16 14:26
        
        software: NCA not validated Helmut 2019-02-16 13:59
        
        no way out for NCA validation? mittyri 2019-02-20 21:22
        
        Default rules mittyri 2019-02-20 21:40

Steady state: Cmin / PTF Helmut 2011-03-08 15:30
- Steady state: Cmin / PTF SDavis 2012-02-06 14:00
  - Steady state: Cmin / PTF Helmut 2012-02-06 14:24
    - Is Cmin an atavism or not? Astea 2019-02-03 22:25
      - Originators | generics (Cmin | Cτ) Helmut 2019-02-04 13:18
        
        Down with Big Brother Astea 2019-02-04 13:51
        
        Down with Big Brother Helmut 2019-02-04 14:43
        
        thoughtcrime Astea 2019-02-04 15:13
        
        blackwhite Helmut 2019-02-04 15:34
        
        animal farm Astea 2019-02-04 15:53

Baseline correction method Sundar.M 2019-01-07 13:54
- Baseline correction method martin 2019-01-08 12:24
  - Baseline correction method Sundar.M 2019-01-08 17:42

Exclusion of PK parameters where less than 3 quantifiable concentrations Babe_Ruth 2018-06-19 18:13
- Reliable estimates? Helmut 2018-06-20 01:12

PK parameters lakshmiprasad 2018-05-17 06:55
- Good reporting practices Helmut 2018-05-17 13:20

half-life in multiple-dosed steady-state BE/BA study? yjlee168 2009-07-14 14:16
- half-life in steady state; WinNonlin Helmut 2009-07-15 15:09
  - no lambda(z), no NCA? yjlee168 2009-07-16 11:53
    - NCA without lambda(z) Helmut 2009-07-16 14:06
      - No rule is the rule - lambda(z) of MD BE yjlee168 2009-07-16 22:17
  - Distinguish accumulation oksanachlebko 2018-01-05 00:10

calculation of cutoff time point in case of multiphasic modified release Biostats 2017-11-25 09:22
- cutoff time point based on PK? Helmut 2017-11-25 13:46
  - cutoff time point based on PK? Biostats 2017-11-26 07:36

BLLOQ (or NQ-Non Quantifiable Concentrations) in PK Concentration data Ashwitha 2017-07-09 15:02

Which Tmax to be consider in case of b.i.d. dosing? maulik963 2016-04-13 08:06
- Which Tmax to be consider in case of b.i.d. dosing? BE-proff 2016-04-13 09:27
  - Which Tmax to be consider in case of b.i.d. dosing? maulik963 2016-04-13 13:09
    - Which Tmax to be consider in case of b.i.d. dosing? Helmut 2016-04-13 13:49
      - Which Tmax to be consider in case of b.i.d. dosing? maulik963 2016-04-16 12:32

0.00 concentration value between two measurable concentrations arl_stat 2016-03-02 10:13
- 0.00 concentration value between two measurable concentrations arl_stat 2016-03-21 12:41
  - “Embedded BQLs” mittyri 2016-03-21 22:17
    - “Embedded BQLs” arl_stat 2016-04-15 08:50

t1/2 prior to Tmax in BE study Dhruv Shah 2016-03-11 03:48
- t1/2 prior to Tmax in BE study jag009 2016-03-11 20:25
  - t1/2 prior to Tmax in BE study Dhruv Shah 2016-03-16 07:01
- t1/2 prior to Tmax in BE study mittyri 2016-03-11 22:20

How to decide partial AUC Compliance 2016-02-11 09:02
- What ’bout science? Helmut 2016-02-11 17:43
  - What ’bout science? Jay 2016-02-16 08:21
    - What ’bout science? Helmut 2016-02-16 13:12

Software validation Helmut 2016-01-28 20:03
- Software validation ElMaestro 2016-01-28 22:33
  - Software validation nobody 2016-01-29 08:16
    - Software validation Shuanghe 2016-01-29 11:08
      - Trilogy? Helmut 2016-01-29 13:31
        
        Trilogy? Relaxation 2016-01-29 18:04
        
        Trilogy? Helmut 2016-01-29 18:51
    - Software validation ElMaestro 2016-01-29 11:20
- Software validation jag009 2016-01-29 22:46

Bi-/multiphasic MR Products – EMA MR-Guideline beman 2015-10-19 12:31
- Bi-/multiphasic MR Products – EMA Helmut 2015-10-19 22:46

Admin contact
23,424 posts in 4,927 threads, 1,671 registered users;
166 visitors (0 registered, 166 guests [including 10 identified bots]).
Forum time: 12:11 CEST (Europe/Vienna)

If you tell the truth you don’t have to remember anything. Mark Twain

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC

Ing. Helmut Schütz