Bioequivalence and Bioavailability Forum

Correct input data to re-calculate results of 3x3x3 study using lm() VStus 2016-08-24 15:42
- Correct input data to re-calculate results of 3x3x3 study using lm() yjlee168 2016-08-25 10:29
  - Correct input data to re-calculate results of 3x3x3 study using lm() VStus 2016-08-26 23:46
    - Correct input data to re-calculate results of 3x3x3 study using lm() BE-proff 2016-09-09 09:32
      - Correct input data to re-calculate results of 3x3x3 study using lm() VStus 2016-09-12 08:41

Validation of bear 2.7.5 in R 3.3.1 on macos10.11.6 mahmoud-teaima 2016-08-25 21:56
- Validation of bear 2.7.5 in R 3.3.1 on macos10.11.6 yjlee168 2016-08-26 08:29
  - Validation of bear 2.7.5 in R 3.3.1 on macos10.11.6 mahmoud-teaima 2016-08-26 15:54
- Validation of software for BE Helmut 2016-08-26 11:20
  - Validation of software for BE mahmoud-teaima 2016-08-26 15:53

CV from CI, pooling, sample size Helmut 2016-07-27 14:09

ANOVA for lambdaz, half life and tmax in bear 2.7.7 mahmoud-teaima 2016-07-20 11:03
- Egypt: Strange requirements Helmut 2016-07-20 12:25
  - Egypt: Strange requirements mahmoud-teaima 2016-07-20 14:12
    - Output is not from Phoenix/Winnonlin mittyri 2016-07-20 17:00
  - ke versus t1/2 d_labes 2016-07-20 16:05
    - ke versus t1/2 Helmut 2016-07-20 16:31
      - ke versus t1/2 d_labes 2016-07-21 14:42
        
        “double“ testing Helmut 2016-07-21 14:54
- tmax in bear 2.7.7 yjlee168 2016-07-20 21:10
  - tmax in bear 2.7.7 mahmoud-teaima 2016-07-20 22:40
    - tmax in bear 2.7.7 yjlee168 2016-07-21 11:11
      - tmax results in R 3.3.1 and spss 20 on macos 10.11.6 mahmoud-teaima 2016-07-27 12:13

PowerTOST on GitHub now d_labes 2016-06-10 11:16
- PowerTOST from GitHub d_labes 2016-06-22 15:10

Possibilty of different CI limits BE-proff 2016-06-07 21:29
- Possibilty of different CI limits ElMaestro 2016-06-07 22:21
  - Possibilty of different CI limits BE-proff 2016-06-07 23:11
    - Possibilty of different CI limits ElMaestro 2016-06-07 23:52

Error in pooledSD(object) jerry 2016-05-11 17:53
- *.csv format in bear yjlee168 2016-05-16 13:50

PowerTOST for steady state BE-proff 2016-04-06 21:39
- PowerTOST for steady state d_labes 2016-04-07 10:54
  - PowerTOST for steady state BE-proff 2016-04-07 15:42
    - RTFM Helmut 2016-04-07 16:09
      - RTFM BE-proff 2016-04-09 20:15
        
        RTFM‼ Helmut 2016-04-10 00:50
        
        RTFM‼ BE-proff 2016-04-10 13:42
        
        RTFM‼ Helmut 2016-04-10 13:48
        
        RTFM‼ BE-proff 2016-04-12 13:36

PowerTOST sample size EMA full replicate Shuanghe 2016-03-07 18:04
- merciless tester! Helmut 2016-03-07 18:56
- PowerTOST sample size EMA full replicate yjlee168 2016-03-07 20:15
- Merciless peer reviewers d_labes 2016-03-08 08:50
- PowerTOST V1.3-4 d_labes 2016-03-09 18:43
- PowerTOST sample size EMA full replicate Astea 2016-03-24 19:34
  - RSABE is not bijective (lengthy answer) Helmut 2016-03-25 14:23
    - RSABE is not bijective (lengthy answer) Astea 2016-03-27 21:07
      - ABEL sample size examples Helmut 2016-03-28 00:42
        
        ABEL sample size: more power! (joke) mittyri 2016-03-28 21:54

Report in R – is that uphill or what? ElMaestro 2016-03-05 23:14
- Report in R – R-Studio & R Markdown d_labes 2016-03-06 13:25
- Old-school Helmut 2016-03-06 15:57
- Report in R – is that uphill or what? yjlee168 2016-03-07 11:52
  - Report in R – is that uphill or what? ElMaestro 2016-03-07 13:36
- Report in R – is that uphill or what? Shuanghe 2016-03-07 17:38
  - To R or not to R d_labes 2016-03-08 07:49

bear v2.7.0 released yjlee168 2015-12-07 09:18
- Suggestion ElMaestro 2015-12-07 10:12
  - Suggestion yjlee168 2015-12-07 10:55
    - Suggestion Helmut 2015-12-07 14:01
      - Suggestion yjlee168 2015-12-07 18:51
- bear v2.7.0 released Astea 2015-12-10 16:36
  - if Clast is zero in bear yjlee168 2015-12-10 17:23
    - if Clast is zero in bear Astea 2015-12-10 20:50
      - if Clast is zero in bear yjlee168 2015-12-11 03:28
        
        if Clast is zero in bear Astea 2015-12-11 09:39
        
        if Clast is zero in bear yjlee168 2015-12-11 17:16
    - bear v2.7.1 yjlee168 2015-12-15 10:21
      - bear v2.7.1 Astea 2015-12-15 19:32
        
        BLLOQ ≠ 0 with measured drug plasma conc. yjlee168 2015-12-15 20:17
        
        BLLOQ ≠ 0 with measured drug plasma conc. Helmut 2015-12-16 01:45
        
        BLLOQ ≠ 0 with measured drug plasma conc. yjlee168 2015-12-16 11:38
        
        BLLOQ ≠ 0 ∀ t > 0 Helmut 2015-12-16 12:40
        
        BLLOQ ∋ { 0, ≈0, BLLOQ{...} ∀ t > 0} yjlee168 2015-12-16 18:22
        
        BLLOQ at first two time ponts, AUC calculation Astea 2016-01-30 17:11
        
        zero-zero with AUC calculation in bear yjlee168 2016-01-30 19:00
        
        BQL rules in bear mittyri 2016-02-01 22:16
        
        BQL rules in bear yjlee168 2016-02-02 10:59
        possible solutions? yjlee168 2016-02-02 21:30
        zero (0), missing (NA), or BLLOQ (0 or NA) in bear yjlee168 2016-02-03 09:04
        
        zero (0), missing (NA), or BLLOQ (0 or NA) in bear mahmoud-teaima 2016-02-08 21:28
        
        Please avoid Full Quotes (“TOFU”)! Ohlbe 2016-02-09 00:51
        
        error message in bear mahmoud-teaima 2016-02-09 04:55
        
        please check your dataset file yjlee168 2016-02-09 06:40
        
        please check your dataset file mahmoud-teaima 2016-02-09 15:00
        
        please check your dataset file yjlee168 2016-02-09 15:38
        
        A possible R bug? yjlee168 2016-02-09 19:14

GUI for Detlew's randomizeBE (bear v2.7.5) yjlee168 2015-12-30 21:05
- GUI for Detlew's randomizeBE (bear v2.7.5) mittyri 2016-01-03 13:04
  - just tried to be as simple as possible yjlee168 2016-01-03 16:37
- GUI for Detlew's randomizeBE (bear v2.7.5) mahmoud-teaima 2016-02-08 02:48
- GUI for Detlew's randomizeBE (bear v2.7.5) mahmoud-teaima 2016-02-08 02:51
  - Installation problems with bear? yjlee168 2016-02-08 05:11
    - Installation problems with bear? mahmoud-teaima 2016-02-08 10:16
      - Installation problems with bear? yjlee168 2016-02-08 10:51
        
        Installation problems with bear? mahmoud-teaima 2016-02-08 11:19
        
        Installation problems with bear? mahmoud-teaima 2016-02-08 12:07
        
        Installation problems with bear? yjlee168 2016-02-08 13:39
        
        Installation problems with bear? yjlee168 2016-02-08 13:32
        
        Installation problems with bear? mahmoud-teaima 2016-02-08 13:53
        
        Installation problems with bear? yjlee168 2016-02-08 14:00
        
        Installation problems with bear? mahmoud-teaima 2016-02-08 14:22
        
        bear? yjlee168 2016-02-08 14:32
        
        bear? mahmoud-teaima 2016-02-08 14:35
        
        demo run with bear yjlee168 2016-02-08 14:49
        
        demo run with bear mahmoud-teaima 2016-02-08 16:00
        
        running bear yjlee168 2016-02-08 20:14
        
        use of my own data with bear mahmoud-teaima 2016-02-08 19:28

PowerTOST sample size FDA full replicate T/R ratio at 85% Shuanghe 2016-01-25 17:49
- PowerTOST sample size FDA full replicate T/R ratio at 85% d_labes 2016-01-26 12:05
  - PowerTOST sample size FDA full replicate T/R ratio at 85% Shuanghe 2016-01-26 12:55
    - PowerTOST sample size FDA full replicate T/R ratio at 85% d_labes 2016-01-26 14:07
    - maximum sample size at which CV? Helmut 2016-01-26 16:31
      - maximum sample size at which CV? nobody 2016-01-26 17:40
      - maximum sample size at which CV? d_labes 2016-01-27 08:41
        
        maximum sample size at which CV? nobody 2016-01-27 09:08
        
        OT: Stop - think -act d_labes 2016-01-27 09:31
      - maximum sample size at which CV? Shuanghe 2016-01-28 12:44
        
        target power 90% Helmut 2016-01-28 13:49
        
        PowerTOST update d_labes 2016-02-01 19:16
        
        #1,000 Helmut 2016-02-01 21:49
        
        OT: post #1,000 d_labes 2016-02-02 21:17
        #1,000 ElMaestro 2016-02-03 16:32
        
        #1,000 Helmut 2016-02-03 16:50
        OT: #1,000 d_labes 2016-02-05 15:50
        
        OT: #1,000 ElMaestro 2016-02-05 17:02
        
        OT: #1,000 d_labes 2016-02-05 19:48
        
        OT: #1,000 ElMaestro 2016-02-06 15:45
        
        OT: #1,000 nobody 2016-02-07 09:50

PowerTOST CV Power EMA 3 periods discontinuity mittyri 2016-02-01 22:33
- Discontinuity = artifact Helmut 2016-02-02 00:23
- 2x Laszlo ElMaestro 2016-02-02 16:28
  - 2x Laszlo Helmut 2016-02-02 16:39
    - 2x Laszlo ElMaestro 2016-02-02 17:09

Error with NCA calculation Rabbaska 2016-01-19 11:53
- λz from two points? Helmut 2016-01-19 13:16