Bioequivalence and Bioavailability Forum

Confidence interval for PK and PD analysis VijithRoy 2021-03-03 08:35
- Confidence interval for PK and PD analysis ElMaestro 2021-03-03 11:15
  - Confidence interval for PK and PD analysis VijithRoy 2021-03-04 10:03

Group Effect alghazam 2021-01-18 22:32
- Single site? Helmut 2021-01-19 11:32

Intra Subject Variability clinicalservices 2021-01-05 08:19
- CVintra in replicate designs (→ 2 IBDs) Helmut 2021-01-05 10:38
- Intra Subject Variability jag009 2021-01-06 00:11

Significant effects Moloko 2020-12-22 11:41
- Significant effects: Don’t worry, be happy! Helmut 2020-12-22 16:27
  - Significant effects: Don’t worry, be happy! Moloko 2020-12-23 13:24

statistical calculation procedures for 4 arm studies Loky do 2020-10-12 23:38
- 4 periods (BE fed & fasting) Helmut 2020-10-12 23:58

Randomization Sequences in fully replicate williams’ design Researcher101 2020-10-10 19:27
- Tricky Helmut 2020-10-10 20:06
  - Tricky ElMaestro 2020-10-10 20:53
    - Tricky Helmut 2020-10-10 21:18
  - Tricky Researcher101 2020-10-11 09:07
    - Very tricky Helmut 2020-10-11 10:57

Treatment effect justification Sivakrishna 2020-10-07 08:15
- Treatment effect justification ElMaestro 2020-10-07 10:19
- statistically significant ≠ clinically relevant Helmut 2020-10-07 11:07
  - statistically significant ≠ clinically relevant Sivakrishna 2020-10-09 10:24
    - Problems with low variability Helmut 2020-10-09 15:04

Adjusted indirect comparisons: Algebra Helmut 2020-10-01 16:41
- Adjusted indirect comparisons: Algebra d_labes 2020-10-01 17:03
  - Adjusted indirect comparisons: Typo Helmut 2020-10-01 17:13
- SE of ∆? Helmut 2020-10-02 14:56
  - SE of ∆? or what? d_labes 2020-10-02 18:54
    - SE of ∆ Helmut 2020-10-02 22:29
      - SE of ∆ d_labes 2020-10-04 10:23

Decision of confidence interval of three period BE study libaiyi 2018-06-26 12:00
- Two tests and one reference Helmut 2018-06-26 13:13
  - Two tests and one reference Brus 2020-08-31 09:58
    - Two tests and one reference ElMaestro 2020-08-31 10:23
    - Two regions: No α adjustment Helmut 2020-08-31 10:26
      - Two regions: No α adjustment Brus 2020-08-31 11:09
        
        Two regions: different populations Helmut 2020-08-31 11:26
- Decision of confidence interval of three period BE study ElMaestro 2018-06-26 22:20
  - Any of two tests and one reference Helmut 2018-06-27 00:33
    - Any of two tests and one reference libaiyi 2018-06-27 08:25
    - Hey wait a moment.... ElMaestro 2018-06-27 08:29
      - Hey wait a moment.... Helmut 2018-06-27 11:45
        
        Pilot or pivotal ? Ohlbe 2018-06-27 12:14
        
        Pilot or pivotal ? ElMaestro 2018-06-27 13:01
        
        Pilot or pivotal ? Ohlbe 2018-06-27 14:13
        
        Pilot or pivotal ? ElMaestro 2018-06-27 14:48
        
        Pilot or pivotal ? Ohlbe 2018-06-27 15:43
        
        Pilot or pivotal ? ElMaestro 2018-06-27 22:13
        
        Pilot or pivotal ? jag009 2018-06-29 20:53
        
        Pilot or pivotal ? ElMaestro 2018-06-29 22:11
        
        Pilot or pivotal ? jag009 2018-07-03 17:38
        
        Hey, hey wait another moment.... d_labes 2018-06-28 19:48
        
        Hey, hey wait another moment.... Helmut 2018-07-03 17:22
        
        Old belives die hard d_labes 2018-07-04 13:28

EMA dataset I, can someone post results? ElMaestro 2020-08-14 20:54
- EMA dataset I, can someone post results? PharmCat 2020-08-14 22:09
  - EMA dataset I, can someone post results? ElMaestro 2020-08-14 22:34
- EMA dataset I (PHX/WNL 8.1) Helmut 2020-08-15 15:00
  - EMA dataset I (PHX/WNL 8.1) PharmCat 2020-08-16 00:57
  - EMA dataset I (PHX/WNL 8.1) ElMaestro 2020-08-19 22:50
    - EMA dataset I (PHX/WNL 8.1) Helmut 2020-08-20 01:05

The grandiose shocker of 2020 ElMaestro 2020-07-22 13:17
- The most obscure post ever Helmut 2020-07-22 13:51
  - Here goes ElMaestro 2020-07-22 14:34
    - Yeah but, no but, yeah but… Helmut 2020-07-22 15:37
      - Yeah but, no but, yeah but… ElMaestro 2020-07-22 17:53
    - Here goes PharmCat 2020-07-29 21:11
- The grandiose shocker of 2020 jag009 2020-07-24 18:52
  - The grandiose shocker of 2020 ElMaestro 2020-07-24 19:01

BA drift Helmut 2020-07-21 15:10

Concentration Statistics - BQL substitution SaraCHenriques 2020-07-01 14:37
- Concentration Statistics - BQL substitution Helmut 2020-07-01 15:27
  - Concentration Statistics - BQL substitution martin 2020-07-02 09:37
    - Data imputation Helmut 2020-07-02 11:15
    - Concentration Statistics - BQL substitution ElMaestro 2020-07-02 13:48
      - Concentration Statistics - BQL substitution martin 2020-07-02 14:52
    - Concentration Statistics - BQL substitution Ben 2020-07-07 16:37
      - BQL in BE and PK modeling Helmut 2020-07-08 10:23
      - Concentration Statistics - BQL substitution ElMaestro 2020-07-08 11:35
      - Roger again mittyri 2020-07-08 12:03

Statistical independence, what is it? I mean really, what is it?? ElMaestro 2020-06-27 21:35
- Die don’t remember the last roll. Really. Helmut 2020-06-28 13:35
  - Die don’t remember the last roll. Really. ElMaestro 2020-06-28 14:45
    - Die don’t remember the last roll. Really. Helmut 2020-06-28 15:36
      - Still none the wiser ElMaestro 2020-06-28 18:20
        
        You’ve lost me now. Helmut 2020-06-28 21:55
        
        Worded differently ElMaestro 2020-06-29 08:30
        
        Still not sure what you are aiming at… Helmut 2020-06-29 16:46
        
        Still not sure what you are aiming at… ElMaestro 2020-06-30 00:55
        
        Confuse-a-Cat Helmut 2020-06-30 11:33
        
        Confuse-a-Cat ElMaestro 2020-06-30 13:07
        
        Confuse-a-Cat Helmut 2020-06-30 14:27
        pseudorandom and linear independence mittyri 2020-07-01 00:04
- Statistical independence, what is it? I mean really, what is it?? martin 2020-07-01 08:40
  - Statistical independence, what is it? I mean really, what is it?? ElMaestro 2020-07-01 09:42
    - Statistical independence, what is it? I mean really, what is it?? martin 2020-07-01 10:07

truncation issues Loky do 2020-06-24 03:23
- EMA: AUC72 for all IR products Helmut 2020-06-24 10:47
  - EMA: AUC72 for all IR products pmohite 2020-06-24 12:08