Bioequivalence and Bioavailability Forum

Sample size determination for William Design Irene_I 2018-07-04 10:27
- Williams’ design (all at once vs. two-at-a-time) Helmut 2018-07-04 11:32
  - Williams’ design (all at once vs. two-at-a-time) Irene_I 2018-07-05 11:04

Power in the pivotal study (EU) valivetiananth 2018-05-31 13:49
- Stop estimating post hoc power! Helmut 2018-05-31 14:45
  - Stop estimating post hoc power! ElMaestro 2018-05-31 15:43
    - Confession Helmut 2018-05-31 17:16
      - Confession ElMaestro 2018-05-31 21:47
        
        Confession Helmut 2018-06-01 00:01
        
        Confession ElMaestro 2018-06-01 08:31
        
        Silly-O-Meter: Syntax Helmut 2018-06-01 13:42
        
        Silly-O-Meter: Syntax ElMaestro 2018-06-01 15:17
  - Stop estimating post hoc power! valivetiananth 2018-06-02 08:52
    - Eligible subjects? Helmut 2018-06-02 13:02
    - Don’t we deserve an answer? Helmut 2018-06-09 15:13

sample size in bioequivalence studies daryazyatina 2017-08-03 09:34
- sample size in bioequivalence studies BE-proff 2017-08-03 09:55
  - sample size in bioequivalence studies daryazyatina 2017-08-03 10:08
- sample size in bioequivalence studies ElMaestro 2017-08-03 10:17
  - sample size in bioequivalence studies daryazyatina 2017-08-03 10:58
    - sample size in bioequivalence studies DavidManteigas 2017-08-03 12:40
      - sample size in bioequivalence studies daryazyatina 2017-08-03 13:46
      - Don’t use the formula by Chow, Shao, Wang! Helmut 2017-08-03 15:37
        
        Don’t use the formula by Chow, Shao, Wang! daryazyatina 2017-08-03 15:52
        Don’t use the formula by Chow, Shao, Wang! DavidManteigas 2017-08-03 16:12
        
        Don’t use the formula by Chow, Shao, Wang! Helmut 2017-08-03 16:33
        
        Don’t use the Book by Chow, Shao, Wang! d_labes 2017-08-16 16:01
    - compromised power Helmut 2017-08-03 16:04
      - compromised power daryazyatina 2017-08-04 08:15
        
        terminology Helmut 2017-08-04 12:41
        
        terminology daryazyatina 2017-08-16 10:12
        
        terminology Helmut 2017-08-16 18:54
- sample size in bioequivalence studies balinskyi 2018-06-03 12:58

Power decrease for the highly correlation of AUCt and AUCinf libaiyi 2018-05-23 08:40
- Relevant: The PK metric with highest CV Helmut 2018-05-23 10:40
  - Relevant: The PK metric with highest CV libaiyi 2018-05-24 10:02
    - Power of 2 independent TOSTs ≈ 2 simultaneous TOSTs with ρ=0 Helmut 2018-05-24 12:54
      - Power of 2 independent TOSTs ≈ 2 simultaneous TOSTs with ρ=0 libaiyi 2018-05-30 03:24

BE parallel studies with more than 2 arms Louis52 2018-04-18 20:18
- BE parallel studies with more than 2 arms ElMaestro 2018-04-18 20:55
  - BE parallel studies with more than 2 arms Louis52 2018-04-23 21:20

Levothyroxine Sample size and study design lakshmiprasad 2018-04-11 15:09
- Levothyroxine Sample size and study design jag009 2018-04-12 22:47
- Levothyroxine Sample size and study design bebac_fan 2018-04-12 22:49
- Levothyroxine Sample size and study design balakotu 2018-04-13 07:15
  - Levothyroxine Sample size and study design lakshmiprasad 2018-04-14 12:55

Power R WinNonLin Yura 2018-01-23 15:02
- Power R WinNonLin d_labes 2018-01-23 15:25
  - Power_TOST in PHX/WNL 6.4+ Helmut 2018-01-23 16:05
    - Power_TOST in PHX/WNL 6.4+ d_labes 2018-01-23 16:54
      - Power_TOST in PHX/WNL 6.4+ Helmut 2018-01-23 17:25
    - Power_TOST in PHX/WNL 6.4+ Yura 2018-01-23 21:55
- Power R WinNonLin pjs 2018-03-23 10:41
  - Power of two stage design d_labes 2018-03-23 17:02
  - Power2Stage / power.2stage() Helmut 2018-03-24 15:49

Within subject variability MaggieSantos 2018-03-15 22:51
- CVw pooled from CVwT and CVwR Helmut 2018-03-16 12:56

Sample size for IVPT study MGR 2018-02-22 06:17

Sample Size Estimation -Replicate design- BE limits cakhatri 2017-11-30 09:44
- Reference-scaling: Don’t use FARTSSIE! Helmut 2017-11-30 10:58
  - Reference-scaling: Don’t use FARTSSIE? Astea 2017-11-30 22:50
    - Reference-scaling: Don’t use FARTSSIE! Helmut 2017-12-01 11:42
      - Reference-scaling: USE PowerTOST Astea 2017-12-01 14:16
        
        Reference-scaling: USE PowerTOST cakhatri 2017-12-04 06:00
        
        Reference-scaling: USE PowerTOST Helmut 2017-12-04 15:07
        
        Reference-scaling: USE PowerTOST cakhatri 2017-12-05 05:33
        
        Use PowerTOST d_labes 2017-12-06 09:52
        
        Use PowerTOST, not Endrényi L, Tóthfalusi L tables mittyri 2017-12-07 16:03
        
        Precision in Endrényi L, Tóthfalusi L tables d_labes 2017-12-07 18:21
        
        Precision of PowerTOST mittyri 2017-12-08 22:56
        
        Precision of PowerTOST Helmut 2017-12-09 17:00
        
        Precision of PowerTOST mittyri 2017-12-09 21:05
        
        Precision of PowerTOST Astea 2017-12-10 00:10
        
        Precision of PowerTOST Helmut 2017-12-10 20:27
        
        Precision of PowerTOST Astea 2017-12-10 21:13
  - Reference-scaling: Don’t use FARTSSIE! pjs 2018-02-09 13:08
    - Reference-scaling: Don’t use FARTSSIE! Helmut 2018-02-09 20:15

Sample size for 4-period 4-sequence crossover BE study Bryony Simmons 2018-02-01 12:16
- function sampleN.TOST of package PowerTOST Helmut 2018-02-01 13:01
  - Alpha adjustment in higher order crossover d_labes 2018-02-01 14:01
    - Deficiencies Helmut 2018-02-01 15:48
      - Deficiencies nobody 2018-02-01 17:10
      - Deficiencies d_labes 2018-02-01 18:57
        
        Deficiencies Relaxation 2018-02-02 11:12
        
        Deficiencies nobody 2018-02-02 12:49
        Deficiencies Helmut 2018-02-02 16:14
        
        Deficiencies Relaxation 2018-02-02 19:41
        
        alpha... where is omega? Astea 2018-02-02 21:45
        
        α and no ω Helmut 2018-02-02 23:39
        
        TIE for NTIDs d_labes 2018-02-04 12:40
        
        TIE for NTIDs Astea 2018-02-04 20:04
        
        TIE for NTIDs Helmut 2018-02-05 01:01
        
        TIE for NTIDs d_labes 2018-02-05 16:40
        
        TIE for NTIDs Helmut 2018-02-05 17:49
        
        TIE for NTIDs d_labes 2018-02-05 22:17
        
        TIE for NTIDs Helmut 2018-02-06 12:34
        
        TIE for NTIDs d_labes 2018-02-05 16:35
        
        bow TIE for NTIDs Astea 2018-02-05 17:52
        
        bow TIE for NTIDs Helmut 2018-02-05 18:10
        
        111.11 for NTIDs Astea 2018-02-05 19:27
        
        111.11 for NTIDs Helmut 2018-02-06 00:12
        
        bow TIE for NTIDs d_labes 2018-02-05 22:33

Sample Size calculation for Clinical trials Mohamed Yehia 2018-02-04 11:42
- Sample Size calculation for Clinical trials Helmut 2018-02-05 15:07

Finding the CI limits Louis52 2018-02-01 19:57
- CV from CI Helmut 2018-02-02 00:56
  - CV from CI Louis52 2018-02-03 17:12
    - CV from CI Helmut 2018-02-03 21:48
      - CV from CI Louis52 2018-02-04 14:38
        
        CV from CI Helmut 2018-02-05 11:39

CVwithin calculation of biperiden CECIF 2018-01-17 20:44
- pooled CV from MR vs. IR Helmut 2018-01-18 16:46
  - pooled CV from MR vs. IR ElMaestro 2018-01-18 17:03
    - pooled CV from MR vs. IR jag009 2018-01-21 03:32
  - pooled CV from MR vs. IR Yura 2018-01-19 10:05
    - TSD: BE in stage 1 Helmut 2018-01-19 12:21
      - TSD: BE in stage 1 Yura 2018-01-19 13:21

Why is the bootstrap not widely used? ElMaestro 2018-01-13 11:06

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