Log in
Register|
drcampos ★ Brazil, 2008-09-09 05:34 (5702 d 06:22 ago) Posting: # 2339 Views: 4,749 |
|
|
Dear All, I would like to know why in a deconvolution procedure (Wagner Nelson or Loo Riegelman) the 100% of fraction absorbed is not achieved in Tmax? For example, plasma concentration versus time figure with Tmax = 3h and fraction absorbed versus time figure with 100% absorved in 8h (only 60 - 70% in 3h (Tmax). Thank you in advance. Daniel Rossi de Campos Brazil |
|
Ohlbe ★★★ France, 2008-09-09 19:22 (5701 d 16:35 ago) @ drcampos Posting: # 2344 Views: 3,897 |
|
|
Dear Dr de Campos, I am not a specialist in this field. But could the answer have a link with this discussion ? (See in particular my message and Helmut's response to it). Regards Ohlbe |
|
drcampos ★ Brazil, 2008-09-09 23:14 (5701 d 12:42 ago) @ Ohlbe Posting: # 2345 Views: 3,911 |
|
|
Dear Ohlbe, Merci beaucoup! Your message and Helmut's response were perfect for the question about Tmax and t1/2! The discussion and examples answered my question. regards, Daniel Rossi de Campos Brazil |
Ing. Helmut Schütz