Bioequivalence and Bioavailability Forum

libaiyi ★ China, 2018-07-03 11:42 (2122 d 04:52 ago) Posting: # 19008 Views: 3,534	Intra-CV in three-treatment, three-period, three-sequence study in SAS [Software] Post reply
	Hi, When I try to calculate the intra-CV of three-treatment, three-period, three-sequence study in SAS, there is only one residual in the output. So, how could I find out the intra-CV between T1-R and T2-R respectively? Could I put only T1 and R or T2 and R in the model to get intra-CV respectively to compare which treatment is better? Thanks in advance.

Helmut
★★★

Vienna, Austria,
2018-07-03 13:26
(2122 d 03:09 ago)

@ libaiyi
Posting: # 19010
Views: 2,995

ISCVs of T1-R and T2-R: Leave-One-Out (IBD)

Post reply

Hi libaiyi,

❝ When I try to calculate the intra-CV of three-treatment, three-period, three-sequence study in SAS, there is only one residual in the output.

Correct – if you use the conventional model, you get only one (pooled) variance.

❝ So, how could I find out the intra-CV between T1-R and T2-R respectively? Could I put only T1 and R or T2 and R in the model to get intra-CV respectively to compare which treatment is better?

See this post. You are on the right track. :-)

Perform two analyses, where in the first you exclude T2 and in the second T1.

—
Dif-tor heh smusma 🖖🏼 Довге життя Україна!
Helmut Schütz

The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes

Intra-CV in three-treatment, three-period, three-sequence study in SAS [Software]

ISCVs of T1-R and T2-R: Leave-One-Out (IBD)