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Back to the forum  Query: 2018-05-25 09:14 CEST (UTC+2h)
 
Ana Cristina
Junior

Brazil,
2018-02-23 00:07

Posting: # 18447
Views: 696
 

 Randomization Crossover Bioequivalence [R for BE/BA]

Dear All,

Could you please give me an advice for the software R use for subject randomization Balanced for sex?

Example: 72 subjects being:
36 for test medication and 36 for reference medication
of the 36 subjects on the test medication: 18 female and 18 male
of the 36 subjects of the reference medication: 18 female and 18 male

Thank you,

Ana Cristina Mazuqueli


Edit: Category changed; see also this post #1. [Helmut]
ElMaestro
Hero

Denmark,
2018-02-23 06:20

@ Ana Cristina
Posting: # 18448
Views: 550
 

 Randomization Crossover Bioequivalence

Hi Ana Cristina,

» 36 for test medication and 36 for reference medication
» of the 36 subjects on the test medication: 18 female and 18 male
» of the 36 subjects of the reference medication: 18 female and 18 male

This can be done in R without too much coding.
But why is the title something with crossover when the description here is not suggestive of such a design? Was the 36+36 (or 18+18+18+18) only applicable for period 1?

“A ten-year, double-blind study from the Mayo Clinic concluded that even in late stages of dementia, the last to go is the lobe of the brain in charge of cafeteria layout.” (Serge Storms/Tim Dorsey).


Best regards,
ElMaestro

- Bootstrapping is a relatively new hobby of mine. I am only 30 years late to the party.
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