Bioequivalence and Bioavailability Forum 12:16 CET

Main page Policy/Terms of Use Abbreviations Latest Posts

 Log in |  Register |  Search

Junior
Junior

Egypt,
2018-01-22 20:33

Posting: # 18253
Views: 1,040
 

 How to calculate N1,N2,N3 and DF in missing Partial replicate [RSABE / ABEL]

Dear All,

I want to know how to calculate N1,N2,N3 and df in partial replicate design (2x3x3) with missing values? I mean lets assume that we have 33 subjects, for Cmax for example, I have 3 subjects that has missing values in 1 periods (n1) and I got another 1 subject with missing value in 2 periods (n2) and for n3, i got all the values

1) Then, how can i calculate the n1,n2,n3 and df that I will use to calculate upper and lower 90% CI?

Thanks.
Activity
 Thread view
Bioequivalence and Bioavailability Forum |  Admin contact
19,190 posts in 4,085 threads, 1,308 registered users;
online 10 (0 registered, 10 guests [including 9 identified bots]).

The aim of science is not to open the door to infinite wisdom,
but to set a limit to infinite error.    Bertolt Brecht

The BIOEQUIVALENCE / BIOAVAILABILITY FORUM is hosted by
BEBAC Ing. Helmut Schütz
HTML5 RSS Feed