Bioequivalence and Bioavailability Forum

jag009
★★★

NJ,
2017-03-02 16:44
(2604 d 10:22 ago)

Posting: # 17121
Views: 3,377

Pulling intrasubject CVs from Full Replicate SAS Routine [RSABE / ABEL]

Hi,

Need some help. Does anyone know how to extract the intrasubject CV from FDA's fully replicate SAS routine for the 90% confidence interval computation? I know I can get such number by plugging in the sample size, T/R Ratio and CI into PowerTost but I want to find out where to extract the number from SAS... I think I asked this question before (from the covariance matrix) but I don't think I have gotten a clear answer...

Thanks
John

jag009 ★★★ NJ, 2017-03-02 20:43 (2604 d 06:23 ago) @ jag009 Posting: # 17122 Views: 2,713	Pulling intersubject CVs from Full Replicate SAS Routine Post reply
	Sorry everyone. I made a typo in the original post. I meant to ask about extracting the intersubject CV, not intra. Thanks John

DavidManteigas ★ Portugal, 2017-03-03 13:14 (2603 d 13:53 ago) @ jag009 Posting: # 17125 Views: 2,667	Pulling intersubject CVs from Full Replicate SAS Routine Post reply
	Hi John, I think you should extract the ods output for G-matrix from proc mixed and use the variances in there to calculate CV's.

Pulling intrasubject CVs from Full Replicate SAS Routine [RSABE / ABEL]

Pulling intersubject CVs from Full Replicate SAS Routine

Pulling intersubject CVs from Full Replicate SAS Routine