rajasekhar
☆    

India,
2017-01-07 08:04
(2637 d 08:50 ago)

Posting: # 16938
Views: 3,252
 

 Replicate designs [RSABE / ABEL]

I am looking for a reference to on what basis we are doing partially and fully replicate studies for high variable drugs (i.e. CV more than 30 %).

My doubt is suppose the drug having the CV is 45%, then how can we decide whether we need to go 3 way or 4 way


Edit: Category changed; see also this post #1. [Helmut]
nobody
nothing

2017-01-07 21:41
(2636 d 19:13 ago)

@ rajasekhar
Posting: # 16940
Views: 2,673
 

 Replicate designs

Hi!
I read somewhere that when the number "45" comes into play you definitely have to go 5.5 periods and sequences. Or something like this. Not really sure...

Kindest regards, nobody
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