khaledazeid
☆    

2016-12-31 11:10
(2671 d 15:30 ago)

Posting: # 16918
Views: 2,083
 

 90% CI of the ratio of the within subject standard deviation [RSABE / ABEL]

Post reply
Dear All,
In the FDA guidance for RSABE for NTI drugs the 90% confidence interval of the ratio of the within subject standard deviation of test product to reference product is required to be less than or equal to 2.5. My question is:
  1. How can i calculate this 90% CI on SAS.
  2. is the F (the value of F distribution) given in the equation:
    [image]
    is the critical F value or else how it could be calculated.

Thanks in advance
 
UA Flag
Activity
 Admin contact
22,993 posts in 4,828 threads, 1,656 registered users;
120 visitors (0 registered, 120 guests [including 4 identified bots]).
Forum time: 03:41 CEST (Europe/Vienna)

Never never never never use Excel.
Not even for calculation of arithmetic means.    Martin Wolfsegger

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5