martin
★★  

Austria,
2015-02-14 11:51
(3358 d 03:33 ago)

Posting: # 14423
Views: 2,346
 

 optimal individualized PK sampling time points [PK / PD]

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Dear all,

I wonder if somebody has experience in defining optimal individualized sampling time points based on an available PopPK model.
  • PopPK model is available providing a predicted PK-curve for a given subject based on his/her covariates
  • These curves can differ heavily between subjects (based on their covariates)
  • For this reason, I think an optimal individualized PK-sampling scheme for a given subject might be useful.
Any ideas and suggestions (e.g. literature) are highly appreciated

Best regards

Martin
 
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