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Snigdhasantra ● 2007-11-11 16:37 (6009 d 15:56 ago) Posting: # 1294 Views: 4,772 |
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Hi.. I am a student and so, if my question sounds no-technical or stupid, kindly understand... I would like to know if we can calculate sample size in case of a study in which only non-parametric tests (chi square test and Z test) will be applied. |
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Helmut ★★★   Vienna, Austria, 2007-11-11 18:59 (6009 d 13:34 ago) @ Snigdhasantra Posting: # 1295 Views: 3,845 |
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Dear Snigdhasantra! ❝ I would like to know if we can calculate sample size in case of a study in which only non-parametric tests (chi square test and Z test) will be applied. In the context of bioequivalence, which kind of PK metric are you testing? The Z test is parametric (based on the normal distribution). For sample size estimation of nonparametric tests you have two options:
Chow, S-C, Shao J, Wang H. Sample Size Calculations In Clinical Research. Marcel Dekker, New York pp 277-292 (2003) — Dif-tor heh smusma 🖖🏼 Довге життя Україна! ![[image]](https://static.bebac.at/pics/Blue_and_yellow_ribbon_UA.png) Helmut Schütz ![[image]](https://static.bebac.at/img/CC by.png) The quality of responses received is directly proportional to the quality of the question asked. 🚮 Science Quotes |
Ing. Helmut Schütz