ramgopi
☆    

India,
2018-12-03 14:30
(2407 d 00:01 ago)

Posting: # 19666
Views: 2,778
 

 Solubility Testing-Shake flask method [Dissolution / BCS / IVIVC]

Post reply
Dear All

could you please any one clarify the formula to calculate the quantity of drug substance dissolved in each buffer for solubility test using shake flask method, does we have to consider sample concentration/weight for the calculation? hope the solubility of the drug doesn't going to change even addition of extra amount of drug after attaining the equilibrium.

I hope this would be a very old topic and enormous data available in web but i couldn't get the exact formula.:-D:-D

Thanks & Regards
Gopinath

Edit: category changed [Ohlbe]
 
UA Flag
Activity
 Admin contact
23,427 posts in 4,929 threads, 1,676 registered users;
44 visitors (0 registered, 44 guests [including 10 identified bots]).
Forum time: 15:31 CEST (Europe/Vienna)

Many people tend to look at programming styles and languages like religions:
if you belong to one, you cannot belong to others.
But this analogy is another fallacy.    Niklaus Wirth

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5