Bioequivalence and Bioavailability Forum

Subject	Author	Posted	Rep.	last R.	Views
Truncated AUC Truncated AUC	Rajinikanth.S	2024-03-20 08:41	1	2024-03-21 13:17	753
Selection of points for Elimination rate constant Don’t include tmax Don’t include tmax Fishy Fishy	ryraman2661	2023-12-23 08:41	4	2023-12-28 12:19	1,181
missing points around tmax Exclude the subject(s) predose sample is missing predose sample is missing predose sample is missing predose sample is missing predose sample is missing predose sample is missing missing points around tmax	Imph	2023-07-02 11:33	8	2023-07-10 16:57	1,737
concentration-time profile with two peaks or more concentration-time profile with two peaks or more concentration-time profile with two peaks or more What does ‘max’ in Cmax mean? What does ‘max’ in Cmax mean? Which software? Which software? tmax ≠ Cmax 🙂 tmax ≠ Cmax 🙂 tmax ≠ Cmax 🙂	Imph	2023-06-27 13:06	9	2023-06-27 18:25	1,503
terminal rate constant estimation terminal rate constant estimation terminal rate constant estimation optimizing schedule for late concentrations > LLOQ	Imph	2022-07-12 17:05	3	2022-07-21 10:21	2,158
AUC · k for variable inter-occasion CL AUC · k for variable inter-occasion CL Changing the regulations: Hope dies last. AUC * k AUC * k AUC * k Ratio/product of two lognormals Not for HVDPs? what about recyclers? Oh dear! Changing the regulations: Hope dies last.	Helmut	2021-09-30 23:31	10	2021-10-04 14:10	2,999
partial AUC partial AUCs in SD partial AUCs in SD partial AUCs in SD partial AUCs in SD Already AUClast: ? ≠ ?	Vishal S	2021-08-02 09:20	5	2021-08-02 12:05	3,109
AUC from 0 to tau at steady state AUC from 0 to tau at steady state AUC from 0 to tau at steady state	martin	2021-06-01 14:43	2	2021-06-01 20:13	1,944
partial AUCs partial AUCs partial AUCs partial AUCs	Helmut	2020-11-05 13:30	3	2020-11-13 00:16	3,144
Fantastic PK parameters and where to find them Fantastic post ?? Rattleback Chatter Reinventing the Hula-Hoop Hula-Hoop references Prof. Keller vs. Yamaoka SHAM(e) math SHAM(e) math OT: Möbius strip OT: Möbius strip More stuff MRT and Gravity duration Fantastic PK parameters and where to find them Cauchy distribution Cauchy distribution Cauchy distribution noncentral normal ratio	Astea	2020-06-12 14:22	17	2020-06-24 09:29	7,709
BLQ handling in BE study where all values in one profile are BLQ BLQ handling in BE study where all values in one profile are BLQ all values in one profile are BLQ (test) BLQ handling in BE study where all values in one profile are BLQ BLQ handling in BE study where all values in one profile are BLQ	Hutchy_7	2019-11-28 15:17	4	2019-11-28 16:44	4,979
“Average” plots “Average” plots “Average” plots Three shades of red Three shades of red Three shades of red Three shades of red	Helmut	2019-04-25 19:06	6	2019-04-26 16:27	5,701
Metrics for absorption Metrics for absorption Metrics for absorption Metrics for absorption Metrics for absorption Metrics for absorption Metrics for absorption Metrics for absorption Metrics for absorption Metrics for absorption Metrics for absorption Simulation framework Simulation framework Conclusion Conclusion & beyond	Helmut	2019-04-15 12:08	14	2019-04-17 15:05	8,350
Baseline correction method Baseline correction method Baseline correction method	Sundar.M	2019-01-07 13:54	2	2019-01-08 16:42	3,608
Exclusion of PK parameters where less than 3 quantifiable concentrations Reliable estimates?	Babe_Ruth	2018-06-19 18:13	1	2018-06-19 23:12	3,543