Bioequivalence and Bioavailability Forum

Subject	Author	Posted	Rep.	last R.	Views
IWRES and NPDE vs time/concentration plots interpretation IWRES and NPDE vs time/concentration plots interpretation	jmt3	2022-04-03 08:25	1	2022-04-05 07:56	1,942
Adjusting weight to reflect group differences in Model Adjusting weight to reflect group differences in Model Adjusting weight to reflect group differences in Model Adjusting weight to reflect group differences in Model	balakotu	2022-03-29 11:24	3	2022-03-30 09:19	2,179
Normal distribution assessment Normal distribution assessment Normal distribution assessment Testing ‘randomness’ Normal distribution assessment	BE-proff	2022-02-20 19:07	4	2022-02-27 17:49	2,208
statistical analysis of William's Design ’Two at a Time’ approach ’Two at a Time’ approach	Ahikal	2021-12-13 17:41	2	2021-12-13 17:06	2,236
Achievement of Steady State Achievement of Steady State: Visual inspection & common sense Achievement of Steady State: Visual inspection & common sense Threshold of % change? Threshold of % change? Keep it simple	arl_stat	2021-07-31 07:42	5	2021-10-20 10:36	4,349
statistical test for Bioavailability studies One-sample t-test One-sample t-test	Loky do	2021-10-13 15:06	2	2021-10-18 07:59	2,241
Randomization 2:1 allocation 2:1 allocation	msmnainar	2021-06-22 14:24	2	2021-06-23 14:49	2,079
DDSolver Issue DDSolver Issue DDSolver Issue DDSolver Issue DDSolver Issue	Laszlo Istvan Orosz	2021-06-09 14:12	4	2021-06-11 07:51	2,358
higher order crossover methodology All dosed subjects have to be analyzed All dosed subjects have to be analyzed All dosed subjects have to be analyzed All dosed subjects have to be analyzed higher order crossover methodology higher order crossover methodology higher order crossover methodology Fed (IBD) → fasting Fed (IBD) → fasting	sweiner	2020-06-30 01:07	9	2021-03-16 15:00	7,640
Degrees of freedom DF in higher-order Xover (again) Degrees of freedom	Mikkabel	2021-03-04 17:20	2	2021-03-04 21:23	2,471
Confidence interval for PK and PD analysis Confidence interval for PK and PD analysis Confidence interval for PK and PD analysis	VijithRoy	2021-03-03 08:35	2	2021-03-04 09:03	2,347
Group Effect Single site?	alghazam	2021-01-18 22:32	1	2021-01-19 10:32	2,338
Intra Subject Variability CVintra in replicate designs (→ 2 IBDs) Intra Subject Variability	clinicalservices	2021-01-05 08:19	2	2021-01-05 23:11	2,327
Significant effects Significant effects: Don’t worry, be happy! Significant effects: Don’t worry, be happy!	Moloko	2020-12-22 11:41	2	2020-12-23 12:24	2,385
statistical calculation procedures for 4 arm studies 4 periods (BE fed & fasting)	Loky do	2020-10-12 23:38	1	2020-10-12 21:58	1,811