Bioequivalence and Bioavailability Forum

Subject	Author	Posted	Rep.	last R.	Views
Requesting data for a publication 📥 ♻️ 🚀 📌 Requesting data for another publication	Helmut	2021-04-08 17:09	1	2021-04-08 17:09	26,171
Group-by-Treatment Interaction	Helmut	2024-04-19 01:26	0		62
Subject effect justification Subject effect justification	Dafni_C	2024-01-17 10:00	1	2024-01-17 12:30	916
Carry over and statistical adjustment in BE computations Carry-over → 🚮 Carry-over → 🚮 Carry-over → 🚮 Carry-over Carry-over Carry-over Carry-over Carry-over more than 20% subject carry over effect investigation carry over effect investigation based on what? carry over effect investigation based on what? Outdated and wrong answers Wrong answer	Achievwin	2023-10-02 20:34	13	2023-10-06 13:20	2,369
Calculation of PE and 90% CI No ‘R1’ and ‘R2’ in replicate designs No ‘R1’ and ‘R2’ in replicate designs Rose is a rose is a rose is a rose No ‘R1’ and ‘R2’ in replicate designs	Brus	2023-06-14 16:34	4	2023-06-19 19:42	1,562
within subject standard deviation in fully replicate design if carry over effect is present within subject standard deviation in fully replicate design if carry over effect is present within subject standard deviation in fully replicate design if carry over effect is present within subject standard deviation in fully replicate design if carry over effect is present within subject standard deviation in fully replicate design if carry over effect is present within subject standard deviation in fully replicate design if carry over effect is present	Ankit Parikh	2023-06-08 13:54	5	2023-06-14 10:37	1,604
average bioequivalence: MLE vs. REML average bioequivalence: MLE vs. REML average bioequivalence: MLE vs. REML average bioequivalence: MLE vs. REML	Mahmoud	2023-03-11 12:21	3	2023-03-16 23:51	1,866
Variance VS Coefficient of variation s² ↔ CV CV ≈ s for low variances CV ≈ s for low variances CV ≈ s for low variances	Imph	2023-02-27 09:09	4	2023-03-06 12:42	2,079
Are Statistical Analysis Plans “required” for Pivotal Studies? SAP vs. part of the clinical protocol SAP vs. part of the clinical protocol Traceability Are Statistical Analysis Plans “required” for Pivotal Studies? Are Statistical Analysis Plans “required” for Pivotal Studies?	Sereng	2023-02-08 18:23	5	2023-02-16 06:55	2,586
Pharmacokinetic and statistical analysis in bioequivalence while maintaining the blind Blinded NCA in Phoenix/WinNonlin Blinded NCA in Phoenix/WinNonlin Blinded NCA in Phoenix/WinNonlin Pharmacokinetic and statistical analysis in bioequivalence while maintaining the blind Phoenix: Locked Workflows Phoenix: Locked Workflows Blind forever? Blind forever?	Imph	2023-02-12 08:31	8	2023-02-15 11:00	2,421
How to calculate Within-subject variability in a replicated BE Models, models!	Brus	2022-12-25 09:21	1	2022-12-25 12:17	2,213
Confidence intervals Confidence intervals	Bebac user	2022-12-19 13:59	1	2022-12-21 21:11	2,326
Observations in a linear model Observations in a linear model Observations in a linear model Observations in a linear model And the Oscar goes to: Replicates! It's all in the df's	Helmut	2022-11-15 10:55	5	2022-11-18 17:28	2,822
Parameter affecting Subject by formulation	Mithu	2022-06-07 09:12	0		1,186
Defining time to concentration threshold Defining time to concentration threshold I prefer interpolation I prefer interpolation Continuous variable → mean	Cytokrom C	2022-04-29 16:24	4	2022-05-01 22:05	2,409