Bioequivalence and Bioavailability Forum

Subject	Author	posted	R’s	last Reply	V’s
Bio-equivalence of IR Tablet against ER Tablet	Jasim Uddin	2018-06-20 13:29	0		55
Three-way crossover BABE Studies Three-way crossover example data set Three-way crossover example data set Three-way crossover example data set Three-way crossover (WinNonlin) Three-way crossover (WinNonlin) Three-way crossover (WinNonlin) Three-way crossover (WinNonlin) Three-way crossover example data set Three-way crossover example data set Three-way crossover example data set Three-way crossover example data set Leave-One-Out (IBD) Leave-One-Out (IBD) Impact of pooled variance (bias, CI) carry (over?)	acfalcao	2007-09-16 22:34	15	2018-06-13 15:31	9,611
Bioequivalence study conditions Amoxicillin/clavulanic acid: if possible, avoid fasting state	Amira Gouda	2018-06-03 16:30	1	2018-06-03 19:47	355
How to demonstrate the bioequivalence of sulodexide	bjkim97	2018-05-30 08:41	0		246
Bioequivalence of IR vs MR tablet Consider 505(b)(2) Pathway Pathway for Softgel vs Tablet Comparison Pathway for Softgel vs Tablet Comparison	heritage	2018-05-05 06:25	3	2018-05-18 16:33	667
BABE for Cefixime Tablets - Canada BABE for Cefixime Tablets - Canada BABE for Cefixime Tablets - Canada Nonlinear PK (less than proportional increase in AUC): lowest strength	Inder	2018-05-12 09:31	3	2018-05-17 12:11	465
Steady State design 5–7 predominant half lives	rajasekharkakarla	2018-05-03 12:28	1	2018-05-03 14:12	487
Diclofenac Powder for oral solution	lakshmiprasad	2018-04-17 13:25	0		338
Diclofenac SR fast or fed state study design Homework Homework Diclofenac SR fast or fed state study design Diclofenac SR fast or fed state study design Diclofenac SR fast or fed state study design Diclofenac SR fast or fed state study design Diclofenac SR fast or fed state study design Diclofenac SR fast or fed state study design Diclofenac SR fast or fed state study design	Norah	2018-02-20 09:14	9	2018-04-13 08:22	2,290
Counterintuitive? Counterintuitive? Counterintuitive? Counterintuitive? Counterintuitive? What is clinically relevant? What is clinically relevant? What is clinically relevant? What is clinically relevant? What is clinically relevant? What is clinically relevant? What is clinically relevant? Korsmeyer–Peppas’ model	nobody	2018-04-03 11:16	12	2018-04-06 23:36	1,586
Postural restriction Postural restriction Postural restriction Postural restriction Postural restriction Postural restriction Postural restriction	lakshmiprasad	2018-03-17 09:20	6	2018-03-27 10:17	1,287
Reasons to go for Partial and Full Replicate Reason to go for Partial and Full Replicate Reasons to go for Full Replicate	kms.srinivas	2018-03-09 05:38	2	2018-03-09 13:17	855
Shorter sampling interval in pilot - Good idea? Shorter sampling interval in pilot - Good idea? Shorter sampling interval in pilot - Good idea? Shorter sampling interval in pilot - Good idea? Shorter sampling interval in pilot - Good idea?	nobody	2018-02-27 19:02	4	2018-02-28 08:36	970
Randomization balanced Randomization balanced	Ana Cristina	2018-02-23 12:50	1	2018-02-23 18:00	727
Choice of comparator Line extension Proportionality and regression Proportionality and regression Line extension Type II variation	Mikkabel	2018-01-23 17:29	5	2018-01-24 11:56	1,530
effect of tabacco on diclofenac metabolism effect of tabacco on diclofenac metabolism Substrate for CYP1A1? Substrate for CYP1A1? effect of tabacco on diclofenac metabolism	Norah	2018-01-22 14:50	4	2018-01-23 08:11	988