Bioequivalence and Bioavailability Forum

Subject	Author	Date	Replies	Last reply	Views
PowerTOST & beyond Small is beautiful Small is beautiful Small is beautiful Small is beautiful Small is beautiful Small is beautiful Small is beautiful Biometrika Power to the students Power to the students Power to the studentinnen Power to the studentinnen Coming soon ...	HS	2010-06-11 18:08	13	2010-07-26 13:59	610
Freedom for replicate bears Freedom for replicate bears Contain does not contain Freedom for replicate bears Freedom incompatible with baseball bats Freedom for replicate bears Freedom to some degree Freedom to some degree FDA loves replicate bears? Cholesky factor ?! Cholesky factor ?! FDA loves replicate bears? FDA loves SAS code? FDA loves SAS code? definitely. SAS? or R? or what? SAS? or R? or what? SAS? or R? or what? SAS? or R? or what? SAS? YES; R? why not? as long as they are useful... New Forum-Category 'bear'? New Forum-Category 'bear'? New Forum-Category 'R for BE/BA' New Forum-Category 'R for BE/BA' Replicated again Replicated again getting decimals getting decimals getting decimals	d_labes	2009-04-17 12:06	27	2010-06-04 01:59	1262
F value for sequence effect F value for sequence effect F value for sequence effect F value for sequence effect F value for sequence effect F value for sequence effect F value; rounding log rounding machine Rounding or not to rounding Rounding or not to rounding Rounding or not to rounding Rounding or not to rounding Rounding or not to rounding Rounding or not to rounding Rounding or not to rounding Type III SS sequence effect -revised Type III SS sequence effect -revised SAS-like Type III SS sequence with bear? New dataset? New dataset? log to 3 decimals guess work log to 3 decimals guess work rounding and presentation of data rounding and presentation of data rounding and presentation of data in R Canadian logs Canadian logs Canadian logs Canadian lost	Pakawadee	2010-05-03 11:48	28	2010-06-03 13:04	737
PowerTOST PowerTOST * Barnstars PowerTOST	d_labes	2010-05-11 08:19	3	2010-05-20 23:08	493
bear v2.5.0 released	yjlee168	2010-05-20 22:34	0		267
Parallel bears meeting at random in infinity Parallel bears meeting at random in infinity Parallel groups in bear - CIs Parallel groups in bear - CIs Parallel groups in bear - CIs Parallel groups in bear - CIs Parallel bears meeting at random in infinity Modelling Parallel bears Modelling Parallel bears Validating vs. WinNonlin... Validating vs. WinNonlin... Validating vs. WinNonlin... Validating vs. WinNonlin... WNL in replicate BE WNL in replicate BE Modelling Parallel bears Modelling Parallel bears Dataset Dataset Dataset Dataset NCA --> Statistical analysis for parallel study NCA --> Statistical analysis for parallel study dilemma Equal variances Equal variances GLM = Equal variances GLM = Equal variances I'm a believer I'm a believer Equal variances gls() for unequal variances? gls() for unequal variances? Sims Sandwich - Simsalabim Sandwich - Simsalabim parametrization of R function rlnorm Mean of log-normal	d_labes	2010-04-22 11:43	38	2010-05-03 16:22	805
Trapezoidal rule - Hmisc Trapezoidal rule - PK package PK package PK Syntax... package PK package PK	d_labes	2010-04-19 13:41	6	2010-04-26 08:04	428
BE code BE code	ElMaestro	2010-03-19 18:50	1	2010-03-19 23:22	360
Approximate² power and sample size	d_labes	2009-11-24 15:55	0		465
non-central t, power, R: non-central t, power, R: non-central t, power, R: non-central t, power, R: non-central t is not the question SAS -> R -> SAS Lost in translation Lost in translation Macacus cynocephalus Lost in translation non-central t is not the question Power of TOST in R Power of TOST (R package MBESS) Power of TOST (R package MBESS) Power of TOST (R package MBESS) The Power at limits Power at limits 2 package MBESS Package MBESS and Power curiosity Package MBESS and Power curiosity Apfelstrudel and EFG 2.01 EFG and another power curiosity EFG and another power curiosity EFG and another power curiosity non-central t, power, R: PASS PASS R code for power Belgian beer ? Another one - R code for power of TROST	ElMaestro	2009-10-03 19:05	29	2009-11-23 19:17	1399
Exact power and sample size, Part I Exact power and sample size, Part II Exact power and sample size, Part III Exact power and sample size, Part IV Backslashes in R-code Backslashes eater Backslashes eater	d_labes	2009-11-23 14:32	6	2009-11-23 15:28	818
R-Code for Power in 2×2 Cross-over Power in Diletti's sample size table Approximate Power Power Calculation for replicate crossover design Power Calculation for replicate crossover design Power Calculation for replicate crossover design Exact Power Exact Power Software validation All the important answers are here! All the important answers are here! All the important answers are here! All the important answers are here! All the important answers are here! 42! SASophylistic power oracle Al Gore Rhythms Al Gore Rhythms Al Gore Rhythms All the important answers are here!	HS	2006-12-28 21:33	18	2009-09-29 23:55	3375
Imbalance + Type III SS = Tricky for the sequence evaluation Imbalance + Type III SS = Tricky for the sequence evaluation Imbalance + Type III SS = Tricky for the sequence evaluation Imbalance + Type III SS = Tricky for the sequence evaluation Sequential phenomena and some R code Sequential phenomena and some R code Default in SAS	ElMaestro	2009-09-07 21:16	6	2009-09-08 21:43	813
Let's skip the fancy nesting syntax! Let's skip the fancy nesting syntax! Let's skip the fancy nesting syntax! Let's skip the fancy nesting syntax! Let's skip the fancy nesting syntax! Let's skip the fancy nesting syntax! Let's skip the fancy nesting syntax! Simple solution Simple solution Type III SS again Type III SS again Type III SS again	ElMaestro	2009-08-26 20:54	11	2009-09-07 19:53	878
release of bear v2.4.0	yjlee168	2009-07-22 06:43	0		723
Calculation of time above MIC Calculation of time above MIC Calculation of time above MIC Calculation of time above MIC Calculation of time above MIC Calculation of time above MIC Therapeutic Occupancy Time Time above MIC (WinNonlin 5.2.1) Time above MIC (WinNonlin 5.2.1) Time above MIC (WinNonlin 5.2.1) Time above MIC (R function) Time above MIC (R function) Time above MIC (R function) Phoenix-WinNonlin 6.0 released 29 May 2009. Phoenix-WinNonlin 6.0 Phoenix-WinNonlin 6.0 - introductory webinars Phoenix-WinNonlin 6.0 - introductory webinars	Aceto81	2008-06-26 16:31	16	2009-06-04 23:40	1673
Multiple groups Multiple groups Multiple groups Multiple groups	janmacek	2009-06-03 10:06	3	2009-06-03 20:09	620
Mean as intercept; model matrices Mean as intercept; model matrices Mean as intercept; model matrices Mean as intercept; model matrices Mean as intercept; model matrices Mean as intercept; model matrices Mean as intercept; model matrices Mean as intercept; model matrices Reparameterization Reparameterization Reparameterization Reparameterized brain	ElMaestro	2009-05-20 20:35	11	2009-05-26 10:28	587
Bear to bear interval with 90% confidence Bear to bear interval with 90% confidence Bear to bear interval with 90% confidence Bear to bear interval with 90% confidence Bear to bear interval with 90% confidence Bear to bear interval with 90% confidence Bear to bear interval with 90% confidence Bear to bear interval with 90% confidence Bear to bear interval with 90% confidence Data set Data set Models (not necessarily nice looking young woman) Models (not necessarily nice looking young woman)	d_labes	2009-04-01 17:00	12	2009-04-07 14:05	785
announce the release of bear v2.3.0 Sample size of bears Sample size of bears	yjlee168	2009-03-09 21:32	2	2009-03-16 08:04	815
Announce the release of bear v2.2.0	yjlee168	2009-02-15 19:29	0		650
R for clinical trials R for clinical trials	martin	2009-01-30 10:21	1	2009-01-30 18:18	785
AUC in Bear AUC in Bear Degenerated trapezoid ;-) Degenerated trapezoid ;-) Bear at Home Bear at Home Bear - statistical summary Bear - statistical summary	d_labes	2008-12-15 15:19	7	2008-12-18 12:13	933
release of bear v2.1.0	yjlee168	2008-12-18 11:44	0		817
Preview: outlier detection with bear v2.1.0 Preview: outlier detection with bear v2.1.0 Preview: outlier detection with bear v2.1.0 Preview: outlier detection with bear v2.1.0 Preview: outlier detection with bear v2.1.0 Preview: outlier detection with bear v2.1.0 Preview: outlier detection with bear v2.1.0 residuals of period 1 residuals of period 1!! residuals of period 1!! Shapiro-Wilk normality test	yjlee168	2008-12-10 12:51	10	2008-12-17 18:28	1507
90% CIs for BE? 90% CIs for BE? 90% CIs for BE? There can be only one! 90% CIs for BE? 90% CIs for BE? 90% CIs for BE? 90% CIs for BE? 90% CIs for BE? 90% CIs for BE? 90% CIs for BE?	yjlee168	2008-11-17 08:52	10	2008-11-17 19:49	1158
bear for R bear for R	thong	2008-11-14 16:12	1	2008-11-17 08:33	904
bear v2.0.1 (upwards) cont'd bear v2.0.1 (upwards) cont'd bear v2.0.1 (upwards) cont'd bear v2.0.1 (upwards) cont'd Imbalance or incomplete data, SASophylistic view Imbalance or incomplete data, SASophylistic view Incomplete cases Incomplete cases Imbalance or incomplete data, SASophylistic view Gold in discussion Gold? Imbalance or incomplete data, WinNonlin5.2.1 Incomplete data, SAS9.2 Missing values, imputation; separate study Incomplete data, SAS9.2, DDF option residual Never belief in any software you haven't written yourself Imbalance or incomplete data, SASophylistic view Imbalance or incomplete data, SASophylistic view Imbalance or incomplete data, SASophylistic view Imbalance or incomplete data, SASophylistic view Imbalance or incomplete data, SASophylistic view Imbalance or incomplete data, SASophylistic view Notification about new posts Notification about new posts 3 Prerequisites for biostatistics 3 Prerequisites for biostatistics	yjlee168	2008-10-26 20:46	25	2008-11-11 14:09	1616
bear v1.0.0 - a data analytical tool for ABE in R bear v1.0.0 for R - first impressions bear v1.0.0 for R - first impressions bear v1.0.0 for R - first impressions bear v1.0.0 for R - first impressions bear v1.0.0 for R... bear v1.0.0 for R... bear v1.0.0 for R... bear v1.0.0 for R - first impressions bear v1.0.0 - a data analytical tool for ABE in R bear v1.0.0 - a data analytical tool for ABE in R bear v1.0.0 - a data analytical tool for ABE in R bear v1.0.0 - a data analytical tool for ABE in R bear v1.0.0 - a data analytical tool for ABE in R bear v1.0.0 - a data analytical tool for ABE in R lambda_z estimation lambda_z estimation lambda_z estimation lambda_z estimation lambda_z estimation lambda_z estimation lambda_z estimation lambda_z estimation lambda_z estimation WinNonlin 5.2.1 vs. 6 beta WinNonlin 5.2.1 vs. 6 beta WinNonlin 5.2.1 vs. 6 beta --> new finding Example 4 in SASophylistic Example 4 in SASophylistic TTT method for lambda_z estimation TTT method for lambda_z estimation TTT method for lambda_z estimation TTT method plus best fit combined AIC or ARS as the best fit criterion? AIC or ARS as the best fit criterion? TTT method for lambda_z estimation TTT method for lambda_z estimation TTT method for lambda_z estimation TTT method for lambda_z estimation TTT method for lambda_z estimation TTT method for lambda_z estimation bear v1.0.0 - a data analytical tool for ABE in R bear v1.0.0 - a data analytical tool for ABE in R bear v1.0.0 - a data analytical tool for ABE in R bear v1.0.0 - a data analytical tool for ABE in R bear v1.0.0 - a data analytical tool for ABE in R bear v1.0.0 - a data analytical tool for ABE in R bear v1.0.0 - a data analytical tool for ABE in R bear v1.0.0 - a data analytical tool for ABE in R bear v1.0.0 - a data analytical tool for ABE in R bear v1.0.0 - a data analytical tool for ABE in R bear v1.0.0 - a data analytical tool for ABE in R bear v1.0.0 - a data analytical tool for ABE in R GLM in R and the power to know GLM in R and the power to know nesting in R? nesting in R? lm in R lm in R lm in R Type III SS in balanced, crossover BE studies? Type III SS in balanced, crossover BE studies? Type III SS in balanced, crossover BE studies? Only balanced, crossover BE studies? Only balanced, crossover BE studies? Only balanced, crossover BE studies? Thread locked	yjlee168	2008-07-12 20:53	66	2008-10-24 11:58	2674
update: bear v1.1.4 for R (a free tool for ABE) update: bear v1.1.4 for R (a free tool for ABE) update: bear v1.1.4 for R (a free tool for ABE) update: bear v1.1.4 for R (a free tool for ABE) update: bear v1.1.4 for R (a free tool for ABE) update: bear v1.1.4 for R (a free tool for ABE) update: bear v1.1.4 for R (a free tool for ABE) Package lee for R update: bear v1.1.4 for R (a free tool for ABE) update: bear v1.1.4 for R (a free tool for ABE) update: bear v1.1.4 for R (a free tool for ABE) update: bear v1.1.4 for R (a free tool for ABE) update: bear v1.1.4 for R (a free tool for ABE) modified function for selection of time points modified function for selection of time points last 3 time points modified function for selection of time points modified function for selection of time points modified code modified code abs(AIC) example example	yjlee168	2008-09-17 13:33	22	2008-10-17 12:30	1512
ivivc for R ivivc for R	yjlee168	2008-04-20 20:02	1	2008-05-10 20:21	1287
stab for R stab for R	yjlee168	2008-05-08 05:57	1	2008-05-08 13:36	1010
Three Way Cross over Dose Proportionality	vijay	2008-04-11 16:36	0		1029
Flaws in evaluation of parallel designs parallel designs (Welch-Satterthwaite in R)	HS	2007-04-17 17:16	1	2007-04-18 17:05	1512