Bioequivalence and Bioavailability Forum • Memantine?

Memantine? [PK / PD]

posted by Chiku – India, 2012-08-02 09:50 (5061 d 03:36 ago) – Posting: # 9017
Views: 10,684

Totally agreed with the data. We also got the same data. what i was trying to say is that Memantine being BCS I drug and low dose 10 mg IR tablet, is not rapidly absorbed (Tmax > 1.5 hr). It slowly absorbs in entire small intenstine and gives Tmax around distal ileum region.

Off topic: why 36 subjects even 20 is suffecient. or you opted parallel design?

Regards

Chiku :-)

Edit: Full quote – once more – removed. Please delete anything from the text of the original poster which is not necessary in understanding your answer; see also this post! [Helmut]

Complete thread:

Factors Affecting Tmax jag009 2012-05-03 23:00 [PK / PD]
- Factors Affecting Tmax luvblooms 2012-05-04 06:04
  - Factors Affecting Tmax Chiku 2012-08-01 14:29
- Factors Affecting Tmax Chiku 2012-08-01 14:26
  - Memantine? Helmut 2012-08-01 15:09
    - Memantine?Chiku 2012-08-02 07:50
      - Memantine! Helmut 2012-08-02 19:57
        
        Memantine! Chiku 2012-08-03 13:06